… Whether or not calcium antagonists are as good … calcium antagonists [7-131. This will be
discussed further in this paper which focuses on lacidipine, a vasoselective calcium antagonist …

… slow onset and long duration of action, fewer side-effects such as reflex tachycardia and
headache, owing to the slow onset … -type calcium channels. This phenomenon explains both the …

… their sites and modes of action on the slow calcium channel, and their effects on various …
calcium antagonists may be put into several pharmacokinetic categories according to their onset …

… , that due attention is paid to the slow onset of action of the newer compounds and its
advantages. It would be more appropriate to characterize them as slow-acting than as long-acting …

… the concept that calcium antagonists are heterogeneous and … calcium antagonist that is
the prototype of the lipophilic dihydropyridines. Of great importance, lacidipine has a slow onset …

… However, in the case of hypertensive emergencies, the strikingly rapid onset of action and
the potent vasodilator properties of the dihydropyridines are clearly different from the activity of …

… Moreover, the combination of a slow onset of action and long duration of action will result
in … In summary, vasoselective CA (DHP) which display a slow onset of action in vitro do not …

… the calcium antagonists together as if they represent a uniform type of agent is erroneous.
The fact that calcium antagonists … the slower onset and longer duration of action of the calcium …

… Onset of action: rap d Time to peak plasma concentration: SI h Bloavallabltlty: 13%. Increased
In padents with hepatic Impairment. Effect of food: administration of nlmodlplne following a …

Drugs classified as calcium antagonists or calcium-channel … calcium antagonists are chemically
diverse, they share the common property of blocking the transmembrane flow of calcium …