Design, synthesis and anticervical cancer activity of new benzofuran–pyrazol-hydrazono-thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis …
HAS Abbas, SS Abd El-Karim - Bioorganic chemistry, 2019 - Elsevier
… –pyrazol-hydrazono-thiazolidin-4-ones (4–22) to be evaluated as anticancer candidates
against the human cervix epithelioid carcinoma cells. Accordingly, the anticancer activity of the …
against the human cervix epithelioid carcinoma cells. Accordingly, the anticancer activity of the …
Synthesis and antiproliferative activity of novel hydrazono thiazolidene and thiazole derivatives bearing rhodanine moiety
MEA Elasasy, DH Elnaggar, NAA Hafez… - Russian Journal of …, 2021 - Springer
… activity of several derivatives has been tested against human breast cancer (MCF-7), human
colon cancer (… In 1 H NMR spectrum of 5a fading of thiazolidine-CH 2 signals demonstrated …
colon cancer (… In 1 H NMR spectrum of 5a fading of thiazolidine-CH 2 signals demonstrated …
Synthesis, antiproliferative activity, molecular docking studies of hydrazone functionalised thioparabanic acid and rhodanine analogues
… As a result of cell culture studies, most of the compounds showed anticancer activity in …
activity on the screened cancer cell lines, and demonstrated stronger antiproliferative activities …
activity on the screened cancer cell lines, and demonstrated stronger antiproliferative activities …
Indole-based hydrazide-hydrazones and 4-thiazolidinones: synthesis and evaluation as antitubercular and anticancer agents
G Cihan-Üstündağ, D Şatana, G Özhan… - Journal of Enzyme …, 2016 - Taylor & Francis
… been evaluated for antiproliferative activity against human cancer cell lines at the National …
activity, here we report the synthesis, structural identification and in vitro antitubercular activity …
activity, here we report the synthesis, structural identification and in vitro antitubercular activity …
[HTML][HTML] … activities of 5-benzylidene-2-[(pyridine-4-ylmethylene) hydrazono]-thiazolidin-4-one and 2-[(pyridine-4-ylmethylene) hydrazono]-thiazolidin-4-one derivatives
A new series of 5-benzylidene-2-[(pyridine-4-ylmethylene)hydrazono]-thiazolidin-4-ones 4a-l
have been synthesized. These compounds were designed by a molecular hybridization …
have been synthesized. These compounds were designed by a molecular hybridization …
Synthesis and anticancer activity of novel nonfused bicyclic thiazolidinone derivatives
D Havrylyuk, B Zimenkovsky… - Phosphorus, Sulfur, and …, 2009 - Taylor & Francis
… to form the thiazolidine ring ( Scheme 3 ). … activity of some of the new nonfused bicyclic
thiazolidinones (4d, 7d, 7c, 8b–8d) at a single concentration of 10 − 5 M against 57 cancer …
thiazolidinones (4d, 7d, 7c, 8b–8d) at a single concentration of 10 − 5 M against 57 cancer …
[HTML][HTML] Novel Thiazolidinone/Thiazolo[3,2-a]Benzimidazolone-Isatin Conjugates as Apoptotic Anti-proliferative Agents Towards Breast Cancer: One-Pot Synthesis …
… In this study, the sensitivity of two different breast cancer subtypes towards the target … growth
inhibitory activity toward certain subtype. MCF-7 is a Luminal A breast cancer cells which is …
inhibitory activity toward certain subtype. MCF-7 is a Luminal A breast cancer cells which is …
Stereoselective synthesis of 2-(2, 4-dinitrophenyl) hydrazono-and (2-tosylhydrazono)-4-oxo-thiazolidine derivatives and screening of their anticancer activity
… the results showed that thiazolidine 4c showed broad anticancer activity against different
cancer cell lines where thiazolidine 4f showed significant activity against RPMI-8226 leukemia. …
cancer cell lines where thiazolidine 4f showed significant activity against RPMI-8226 leukemia. …
Hydrazonoyl halides as precursors for synthesis of bioactive thiazole and thiadiazole derivatives: synthesis, molecular docking and pharmacological study
… activity of the newly synthesized compounds and to perform a molecular docking study to
interpret their activity. … The in-vitro anti-tumor activity of the tested compounds was evaluated in …
interpret their activity. … The in-vitro anti-tumor activity of the tested compounds was evaluated in …
New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies
SS Abd El-Karim, YM Syam, AM El Kerdawy… - Bioorganic …, 2019 - Elsevier
… The cancer chemopreventive activity of various synthetic and natural … activities extend to
several mammalian cancer cell lines in vitro and in xenograft models [25]. Their cytotoxic activity …
several mammalian cancer cell lines in vitro and in xenograft models [25]. Their cytotoxic activity …