… of EGFR alterations, we analyzed patient survival for pan-cancer and for each cancer type
… When all tumors were analyzed together, patients with any EGFR alteration had significantly …

… EGFR aberrations. In this study, we examined specimens from the autopsy of a patient with
EGFR-… Each metastatic lesion was analyzed for EGFR aberrations and compared. All the …

… We hypothesized that genetic aberration of the EGFR pathway would identify patients …
responsive to anti-EGFR therapies. We aimed to determine if analysis of EGFR signaling pathway …

… factor receptor (EGFR) family consists of four members: HER1 (EGFR), … Aberrations in
EGFR family members play a role in the development and progression of many human cancers …

… In conclusion, we have found correlations between EGFR gene variants and somatic
aberrations of both EGFR and CDKN2A/B. We believe these variants may have a driving effect on …

… To distinguish between aberration patterns of tumor samples with and without a mutation
in the EGFR-gene, we defined the mutation status as target and ranked all aberrations …

… Focusing on chromosome 7 (chr7), we show that focal high-level amplification at the EGFR
gene is associated with activation of EGFR itself whereas broad lower-level amplification of …

… Epidermal growth factor receptor (EGFR) is commonly affected in cancer, … of EGFR/EGFRvIII
aberrations. While the exact diagnostic, prognostic and predictive value of such EGFR …

… cancer (NSCLC). We sought to investigate EGFR aberrations in patients with diverse advanced
cancers… are found in only a small subset of patients, as seen with EGFR aberrations in …

… other derangements of EGFR signaling are … EGFR aberrations, or “multiple whammy”
tumors. The finding that all of these different mechanisms activate EGFR signaling in lung cancers …