Exploitation of gene expression and cancer biomarkers in paving the path to era of personalized medicine

HFM Kamel, HSAB Al-Amodi - Genomics, Proteomics and …, 2017 - academic.oup.com
… toward “individualized biomarker-driven cancer therapy” or “… the current landscape of cancer
biomarkers and their role in … novel cancer biomarkers in improving the outcome of cancer

Common cancer biomarkers

CF Basil, Y Zhao, K Zavaglia, P Jin, MC Panelli… - Cancer research, 2006 - AACR
… were selected from a basis of 332 already proposed biomarker genes that were included in
… We compared previously the gene expression profile of normal renal epithelium with that of …

Gene expression profiling reveals novel biomarkers in nonsmall cell lung cancer

A Sanchez‐Palencia, M Gomez‐Morales… - … journal of cancer, 2011 - Wiley Online Library
gene expression profiling technology is having an increasing impact on our understanding
of lung cancer … the phenotypic heterogeneity and genetic diversity of lung cancer. Microarray …

[HTML][HTML] Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel

A Amaro, AI Esposito, A Gallina, M Nees… - Cancer and Metastasis …, 2014 - Springer
expression of each gene was determined in prostate cancer (… , we used gene expression
data of prostate cancers of the … data set sampling 281 prostate cancers analyzed by microarray …

CircRNAs and cancer: biomarkers and master regulators

E Arnaiz, C Sole, L Manterola, L Iparraguirre… - Seminars in cancer …, 2019 - Elsevier
… role as master regulators of gene expression (discussed below), perhaps the most interesting
feature of circRNAs are their potential as novel biomarkers for cancer and other diseases. …

Meta-analysis of colorectal cancer gene expression profiling studies identifies consistently reported candidate biomarkers

SK Chan, OL Griffith, IT Tai, SJM Jones - Cancer Epidemiology Biomarkers & …, 2008 - AACR
… Many genes were consistently reported as differentially expressed in multiple studies and this
… candidate biomarkers we present here will be a valuable resource to the colorectal cancer

[HTML][HTML] SurvExpress: an online biomarker validation tool and database for cancer gene expression data using survival analysis

R Aguirre-Gamboa, H Gomez-Rueda… - PloS one, 2013 - journals.plos.org
… types where many datasets were found for the same gene expression platform, we also
provide a merged meta-base. In meta-bases, datasets were quantile normalized; probesets …

[HTML][HTML] Identification of a multi-cancer gene expression biomarker for cancer clinical outcomes using a network-based algorithm

E Martinez-Ledesma, RGW Verhaak, V Treviño - Scientific reports, 2015 - nature.com
… For biomarkers specific to a cancer-type, the negative … multi-cancer biomarker, we used
the NLLRT of a reference cancer-type minus the range of the NLLRT from the remaining cancer-…

Discovery of prostate cancer biomarkers by microarray gene expression profiling

KD Sørensen, TF Ørntoft - Expert review of molecular diagnostics, 2010 - Taylor & Francis
gene expression profiling Microarray expression profiling of tumor samples for biomarker
the assumption that gene expression patterns are major determinants of cancer cell behavior. …

[HTML][HTML] Gene expression profiles of non-small cell lung cancer: survival prediction and new biomarkers

K Välk, T Vooder, R Kolde, MA Reintam, C Petzold… - Oncology, 2011 - karger.com
… According to the gene expression profiles, we identified 2 distinct cancer groups (referred to
herein as group 1 and group 2). Based on their expression profiles, group 2 (blue) was more …