Resistance to multiple chemotherapeutic agents in human cancer cells
MM Gottesman, I Pastan - Trends in pharmacological sciences, 1988 - cell.com
Human cancer cells selected for resistance to multiple hydrophobic cytotoxic drugs express
the cell surface P-glycoprotein, which is the product of the MDRl gene. In this review Michael …
the cell surface P-glycoprotein, which is the product of the MDRl gene. In this review Michael …
The effectiveness of various chemotherapeutic agents in cancer treatment
… Though chemotherapeutic agents have effect on cancer cells, their usage … chemotherapeutic
agents in less dosage with higher dosage of polyphenols are less cytotoxic to normal cells. …
agents in less dosage with higher dosage of polyphenols are less cytotoxic to normal cells. …
Optimal delivery of chemotherapeutic agents in cancer
P Dua, V Dua, EN Pistikopoulos - Computers & Chemical Engineering, 2008 - Elsevier
… to the normal cells. In this paper, two models for cancer chemotherapy are considered and
the … The first model considers the case when the chemotherapeutic agents kill cancer cells …
the … The first model considers the case when the chemotherapeutic agents kill cancer cells …
Enhanced in vitro selective toxicity of chemotherapeutic agents for human cancer cells based on a metabolic defect
PH Stern, RM Hoffman - JNCI: Journal of the National Cancer …, 1986 - academic.oup.com
… of administering chemotherapy on the basis of metabolic differences between normal and
cancer cells. Perhaps this approach will finally lead to effective chemotherapy for many types …
cancer cells. Perhaps this approach will finally lead to effective chemotherapy for many types …
Advances in delivery of chemotherapeutic agents for cancer treatment
… is the preferred choice in case of metastatic cancers [2]. Chemotherapy leads to the suppression
of cell division which is a characteristic feature of cancer cells. However, rapidly dividing …
of cell division which is a characteristic feature of cancer cells. However, rapidly dividing …
[HTML][HTML] Diversity of the senescence phenotype of cancer cells treated with chemotherapeutic agents
A Bojko, J Czarnecka-Herok, A Charzynska… - Cells, 2019 - mdpi.com
… of several cancer cell lines treated with different anticancer drugs using a set of common
senescence markers. Our results point to a cell type and drug diversity in the cancer cell …
senescence markers. Our results point to a cell type and drug diversity in the cancer cell …
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
… of PUMA by chemotherapeutic agents is abolished in p53-deficient lung cancer cells.
PUMA expression resulted in potent growth suppression of lung cancer cells and suppressed …
PUMA expression resulted in potent growth suppression of lung cancer cells and suppressed …
Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells
B Agarwal, S Bhendwal, B Halmos, SF Moss… - Clinical Cancer …, 1999 - AACR
… for cancers. We therefore studied whether combinations of the HRI lovastatin with standard
chemotherapeutic agents would augment apoptosis in colon cancer cells. In the colon …
chemotherapeutic agents would augment apoptosis in colon cancer cells. In the colon …
Chemotherapeutic agents in low noncytotoxic concentrations increase immunogenicity of human colon cancer cells
… concentrations of chemotherapeutic agents, a … tumor cell-based and DC-based vaccines.
Our results also suggest a new mechanism of how a very low dose of chemotherapeutic agents …
Our results also suggest a new mechanism of how a very low dose of chemotherapeutic agents …
Addressing drug resistance in cancer with macromolecular chemotherapeutic agents
… Given the success of the macromolecular chemotherapeutics against drug-resistant
cancer cell lines, we sought to further evaluate if multiple treatments with the polymer caused …
cancer cell lines, we sought to further evaluate if multiple treatments with the polymer caused …
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