BACKGROUND & AIMS: Identification and purification of cancer stem cells (CSCs) could lead
to new therapeutic targets, but their heterogeneous expansion is an obstacle to their study. …

… These results demonstrated that metformin can enhance the cytotoxicity of chemotherapeutic
agents on drug-resistant cancer cells. Autophagy, as a type of cell death, degrades cellular …

… adaptations that compromise the effectiveness of chemotherapy. In response to nutrient …
cancer cells decreases but chemotherapeutic drugs are more effective against proliferating cells. …

… cancer therapy, various ROS-generating agents are currently in clinical trials, either as single
agents … stress for the efficacy of standard chemotherapeutic agents. In this context, we have …

Pentosan is a new chemotherapeutic drug which is currently in Phase I clinical trials. In our
experimental systems, in vivo, pentosan inhibits the growth of the highly metastatic MAT‐…

… deliver chemotherapeutic agents to cancer cells, minimizing the undesirable side effects. …
chemotherapeutic agents to molecular targets overexpressed on the surface of tumor cells. In …

… Despite being non-specific, chemotherapy has a stronger effect on cancer cells because
cancer cells usually develop and divide more quickly than normal cells. In this treatment, one or …

… For this reason, DNA has become a critical target in cancer chemotherapy. Indeed, many
of the antitumour agents currently in the cancer armamentarium are DNA-interactive. Among …

… a novel proapoptotic agent that … cancer cell lines. We compared these effects with those of
13-cis-retinoic acid, a chemoprevention agent, and with the cytotoxic chemotherapeutic agents …

… to chemotherapy agents in human gastric cancer cells. … to chemotherapy. Effective blockade
of the Stat3 pathway remarkably sensitized gastric cancer cells to chemotherapeutic agents. …