… However, plethora of other genes, involved in many aspects of cell life, increase the enormous
complexity of mechanism of action of individual coordination compounds in cancer cells. …

… Hence, our results are suggestive that both coordination compounds presented here
exhibit good therapeutic potential, affecting the expression of proteins typically deregulated in …

… )] and [Cu(ida)(4met-phen)] showed the strongest cytotoxic activity against cancer cell
lines and therefore, those compounds are good candidates to test its antitumor activity in vivo. …

… of coordination compounds based on Indazole-3-carboxylic acid. These materials show
interesting anti-cancer … for ligand and compounds 2 and 3 in three different cancer cell lines, B16-…

… cancers and its down regulation inhibits breast cancer cell … suggest that dithio(peroxo)thioate
compounds have potent … expressing MCF7 and T47D breast cancer cell growth as well as …

… as anti-cancer agents to substitute … cell apoptosis. These results hence indicate that metal
screening with a ligand is important as it may allow identifying coordination compounds with …

… use of coordination compound-based zinc oxide (ZnO) nanoparticles (NPs) for the treatment
of triple negative breast cancer cells (TNBrCa). As BrCa is one of the most prevalent cancer …

… have received limited attention compared with organic compounds. Much of the attention
has … transport of metal compounds across cell membranes and future roles for metallo-drugs. …

… differences from the reactions that take place in living cells. 5 The compounds that have
one or more labile ligands in their coordination spheres, such as chloride ion or a carboxylate, …

… ligand environment, this Section focuses on mononuclear Zn II coordination compounds
exhibiting significant cytotoxicity against cancer cell lines. An analysis of the structure – activity …