… small population of drug resistant cancer cells poses another … These drug resistant cancer
cells also contribute to cancer … cancer progenitor cells or drug resistant cancer cells render …

… Rather, this Review focuses on the mechanisms that enable the survival of cancer cells
during drug treatment and on current research efforts to identify and overcome underlying …

… the gene amplification in some tumoral cells, including leukemia cause the drug resistance
to Methotrexate. The cancer cells cause the drug resistance via providing the multiple copies …

… elude treatment has yielded a wealth ofinformation about why these therapies fail and is
beginning to yield valuableinformation about how to circumvent drug resistance in cancer cells …

… by which cells acquire pleiotropic drug resistance appears to … breast cancer cells. J Clin
Invest 70: 351-360, 1982. 28. … of resistance to methotrexate in human breast cancer cells: lack of …

… cancer cell drug resistance. Wang and coworkers [26] treated bladder cancer T24/ADM cells
by … They found that the IC50 of osthole was 76.5 μM and it was not toxic to the cells at the …

… of cells to drugs, this study clearly shows that results derived from established cancer cell
lines … drug resistance in cancer should be interpreted with caution. Investigators using these …

… in the intrinsic and acquired resistance of cancer cells to current cancer therapies. We …
cancer cells during cancer progression that may contribute in a crucial manner to drug resistance …

… Other models used paradigm prokaryotic organisms, such as Escherichia coli, in an effort
to detect mutations in drug-resistant cancer cells and investigate their role in drug …

… drug resistance to sunitinib in NSCLC A549 cells, we found that extracellular ATP can be
internalized by cancer cells … ’s roles in cancer cell growth, survival and drug resistance were …