… the metabolic differences between cancer and normal cells … cancer cell biology but also
provide an important basis for the … eliminate cancer cells by targeting their unique metabolism. …

… cells. Here, we describe key features of the metabolic transformation of cancer cells, which
… reprogramming, and the deregulation of lipid metabolism, highlighting the notion that these …

… Cancer cell metabolism is characterized by an enhanced … The persistent activation of
aerobic glycolysis in cancer cells … may present a new basis for cancer treatment. Accordingly, …

… -stromal metabolic coupling, in which cancer cells induce … cancer-associated fibroblasts
provide recycled nutrients to epithelial cancer cells, "fueling" oxidative mitochondrial metabolism …

The precise mitochondrial alterations that underlie the increased dependence of cancer
cells on aerobic glycolysis for energy generation have remained a mystery. Recent evidence …

… (TCA) cycle, and serine biosynthesis in cancer cells and tumor xenografts. We show for the
… as the central metabolic basis of NAMPT inhibition responsible for ATP depletion, metabolic …

… core cellular metabolism and provide support for the three basic needs of dividing … cellular
redox status (Fig. 1). To meet these needs, cancer cells acquire alterations to the metabolism …

… to gain insight into the metabolic behavior of cancer cells using only minimal information …
Next, using these tabulated requirements as a basis, we perform stoichiometric analyses to …

… In conclusion, identifying and understanding complex metabolic interactions is a basis for
deciphering novel metabolic vulnerabilities of cancer cells. WIREs Syst Biol Med 2018, 10:…

… cell that responds to low ATP levels compared to AMP levels and low nutrient levels by down
regulating cell growth, lipid and protein metabolism. … deficient kidney cancer cells and this …