ROS stress in cancer cells and therapeutic implications
H Pelicano, D Carney, P Huang - Drug resistance updates, 2004 - Elsevier
… kill cancer cells through ROS-mediated mechanisms. This article reviews ROS stress in cancer
cells… Because cancer cells produce high levels of ROS and are under increased oxidative …
cells… Because cancer cells produce high levels of ROS and are under increased oxidative …
ROS homeostasis and metabolism: a dangerous liason in cancer cells
E Panieri, MM Santoro - Cell death & disease, 2016 - nature.com
… by sustained ROS production, cancer cells have developed an efficient mechanism of ROS
… Therefore, the dependency of cancer cells from their antioxidant systems represents a …
… Therefore, the dependency of cancer cells from their antioxidant systems represents a …
Cancer cell killing via ROS: to increase or decrease, that is the question
J Wang, J Yi - Cancer biology & therapy, 2008 - Taylor & Francis
… therapeutic approaches for cancers, including chemotherapy… cell death, therefore ROS are
also used to kill cancer cells. … that cancer cells exclusively produce more ROS than normal …
also used to kill cancer cells. … that cancer cells exclusively produce more ROS than normal …
[HTML][HTML] Production and detection of reactive oxygen species (ROS) in cancers
D Wu, P Yotnda - Journal of visualized experiments: JoVE, 2011 - ncbi.nlm.nih.gov
… Detection of protein oxidation investigates the total effects of all ROS produced by the
studied cells; here the intensity of the signal obtained represents the amount of ROS produced. …
studied cells; here the intensity of the signal obtained represents the amount of ROS produced. …
Reactive oxygen species (ROS): key components in cancer therapies
BM Sahoo, BK Banik, P Borah… - Anti-Cancer Agents in …, 2022 - ingentaconnect.com
… of ROS involved in different pathways of killing cancer cells during the development of anti-…
their effect on cancer cells by producing these reactive oxygen species during their metabolic …
their effect on cancer cells by producing these reactive oxygen species during their metabolic …
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells
IR Indran, MP Hande, S Pervaiz - Cancer research, 2011 - AACR
… not only reduces the basal cellular reactive oxygen species (ROS) levels but also inhibits
endogenous ROS production in response to stimuli that induce intracellular ROS generation. …
endogenous ROS production in response to stimuli that induce intracellular ROS generation. …
Understanding the mechanism of action of melatonin, which induces ROS production in cancer cells
J Florido, C Rodriguez-Santana, L Martinez-Ruiz… - Antioxidants, 2022 - mdpi.com
… This review described the possible pathways involved in ROS production by melatonin in
cancer cells. These mechanisms include, besides melatonin receptors, sirtuins and Akt …
cancer cells. These mechanisms include, besides melatonin receptors, sirtuins and Akt …
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
D Trachootham, J Alexandre, P Huang - Nature reviews Drug discovery, 2009 - nature.com
… An increase in ROS is associated with abnormal cancer cell … elevation of ROS production
or to a decline of ROS-scavenging … Because the increase of ROS in cancer cells may play an …
or to a decline of ROS-scavenging … Because the increase of ROS in cancer cells may play an …
Reactive oxygen species in cancer cells: live by the sword, die by the sword
PT Schumacker - Cancer cell, 2006 - cell.com
… , where mutations in mitochondrial DNA (which encodes specific subunits of the ETC)
have been linked to increases in ROS production and tumor progression in prostate cancer …
have been linked to increases in ROS production and tumor progression in prostate cancer …
ROS and energy metabolism in cancer cells: alliance for fast growth
SW Kang, S Lee, EK Lee - Archives of pharmacal research, 2015 - Springer
… NADPH oxidase and the ROS-eliminating antioxidant enzymes, both of … between ROS
and energy metabolisms in cancer cells. … production and elimination systems will bring a new …
and energy metabolisms in cancer cells. … production and elimination systems will bring a new …
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