… inhibitors targeting STAT3 activation have … cancer. This systematic review discusses the
advances in the discovery of the STAT3 pathways and drugs targeting STAT3 in breast cancer. …

… the Stat3 signaling pathway plays an important role in regulating prostate cancer cell growth
… we propose that activation of Stat3, a critical mediator for prostate cancer cell growth, occurs …

… STAT3 pathway in cancer. We review the mechanisms of STAT3 pathway regulation and the
consequent cancer … p-STAT3 in gastric and oral cancer cells. Moreover, after treatment with …

… STAT3 is both a transcription activator and an oncogene that … indicates that STAT3 is
persistently activated in several cancers, … in cancer cell proliferation, invasion and migration, …

… Stat3 in basal-like breast cancer cells, we also transplanted mice with SUM159PT cells in
which STAT3 … Tumors derived from cells with Stat3 knockdown displayed substantial delay in …

… involved in cancer cell death, we also detected whether death receptor pathway participated
in AG490 and STAT3 induced CRC cells apoptosis. Death inducing signalling complex …

… However, whether Andro could inactivate other survival signaling pathways to … STAT3
pathway and evaluate whether suppression of STAT3 activity by Andro could sensitize cancer cells …

… We reasoned inhibiting Stat3 pathways in ovarian and breast cancer cell lines may block …
cell death in these cancer cells. In this study we examine the importance of the Stat3 pathway …

… cancer-initiating cells or cancer stem-like cells and examines the role of STAT3 pathway in
these cancer stem-like cells. … -like colorectal cancer cells expresses STAT3 phosphorylation. …

… survival and tumor metastasis pathways [… pathway is activated in both renal cancer cell lines,
suggesting that the activation of the AKT/mTOR pathway is a common event in renal cancer. …