New insights into the mechanisms for photodynamic therapy-induced cancer cell death

JO Yoo, KS Ha - International review of cell and molecular biology, 2012 - Elsevier
… This review describes the cellular and molecular signaling pathways of PDT-induced cancer
cell death, focusing on how the signaling pathways and cross talk between pathways are …

Therapy-induced senescence in cancer

JA Ewald, JA Desotelle, G Wilding… - … of the National Cancer …, 2010 - academic.oup.com
… the inductiontherapy in cancer cells in which apoptotic pathways are disabled ( 20 ). In
this review, we discuss current information on treatments that induce senescence in cancer cells

[HTML][HTML] Cancer stem cells: therapeutic implications and perspectives in cancer therapy

L Han, S Shi, T Gong, Z Zhang, X Sun - Acta Pharmaceutica Sinica B, 2013 - Elsevier
… According to the theory, a minority population of cancer cells is capable of self-renewal and
… of Wnt/β-catenin pathway in cancer cells or CSCs, which induces neoplastic proliferation 83 . …

Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells

UE Martinez-Outschoorn, Z Lin, YH Ko, A Goldberg… - Cell Cycle, 2011 - Taylor & Francis
… combination acutely induces the Warburg effect (aerobic glycolysis) in MCF7 cancer cells,
abruptly cutting off their ability to use their fuel supply, effectively killing these cancer cells. …

[HTML][HTML] Metabolic alterations in cancer cells and therapeutic implications

N Hammoudi, KBR Ahmed, C Garcia-Prieto… - … journal of cancer, 2011 - ncbi.nlm.nih.gov
… Elucidation of the metabolic differences between cancer and normal cells and the …
cancer cell biology but also provide an important basis for the development of new therapeutic

Targeting microRNAs in epithelial-to-mesenchymal transition-induced cancer stem cells: therapeutic approaches in cancer

M Garg - Expert opinion on therapeutic targets, 2015 - Taylor & Francis
… as a new player in the induction and regulation of EMT. … of EMT-induced CSCs with therapeutic
resistance, tumor growth … targeting of EMT-induced CSCs through altered expression of …

MYC-induced cancer cell energy metabolism and therapeutic opportunities

CV Dang, A Le, P Gao - Clinical cancer research, 2009 - AACR
… for the proliferation of human B lymphoid tumor cells and the prostate PC3 cancer cell lines,
suggesting that it could be a key target for therapy (38). Furthermore, antisense reduction of …

Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers

RS Roberson, SJ Kussick, E Vallieres, SYJ Chen… - Cancer research, 2005 - AACR
… the parental cells in their transcription profile. We show that these escaped H1299 cells
We also present evidence that ACS occurs in vivo in human lung cancer following induction

Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3

WP Tsang, TT Kwok - Apoptosis, 2008 - Springer
… , the cells that do not express caspase-3. Therefore, let-7a by … modulating drug-induced cell
death in human cancer cells. … -induced apoptosis and drug sensitivity of human cancer cells. …

Role of chemopreventive agents in cancer therapy

T Dorai, BB Aggarwal - Cancer letters, 2004 - Elsevier
… Similarly, curcumin was found to induce radiosensitization of prostate cancer cells through
the … effects by overcoming therapy-induced prosurvival gene expression in several cancers. …