How the Warburg effect supports aggressiveness and drug resistance of cancer cells?

P Icard, S Shulman, D Farhat, JM Steyaert… - Drug Resistance …, 2018 - Elsevier
… In the current review, we attempt to explain why cancer cells … sustains tumor cell proliferation
and aggressiveness (… effect also promotes many tumor characteristics that result in …

Phenotypic changes of acid-adapted cancer cells push them toward aggressiveness in their evolution in the tumor microenvironment

M Damaghi, R Gillies - Cell Cycle, 2017 - Taylor & Francis
… on cancer evolution and therapy. We show acid adapted cancer cells acquire aggressive and
… We also show rearrangement of cancer cells in their tumor society as a defensive strategy …

Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1α-dependent manner in pancreatic cancer cells

O Hashimoto, K Shimizu, S Semba, S Chiba, Y Ku… - Pathobiology, 2011 - karger.com
cell surface marker CD133 in human brain tumors, such as medulloblastoma and glioblastoma
[15–17]. The present study hypothesizes that cancer cells … pancreatic cancer cells was …

PTPN13/PTPL1: an important regulator of tumor aggressiveness

G Freiss, D Chalbos - … Current Medicinal Chemistry-Anti-Cancer …, 2011 - ingentaconnect.com
… Thus, we hypothesized that PTPL1 regulates breast cancer cell aggressiveness through
inactivation of the Src kinase pathway. The inhibition of Src kinase expression drastically …

[HTML][HTML] Nutritional exchanges within tumor microenvironment: impact for cancer aggressiveness

G Comito, L Ippolito, P Chiarugi, P Cirri - Frontiers in oncology, 2020 - frontiersin.org
cells, so that they can give efficient support for cancer cell proliferation and spreading. A
mandatory role in tumor … In tumors, cytokines released by cancer cells convert fibroblasts into a …

Bisphenol A induces a profile of tumor aggressiveness in high-risk cells from breast cancer patients

SH Dairkee, J Seok, S Champion, A Sayeed… - Cancer research, 2008 - AACR
tumor aggressiveness and poor patient outcome. [Cancer Res 2008;68(7):2076–80] …
Although reports on cancer cells themselves have described the growth-stimulating effects …

Changes in tissue fluidity predict tumor aggressiveness in vivo

F Sauer, S Grosser, M Shahryari, A Hayn… - Advanced …, 2023 - Wiley Online Library
… In the following study, we combine vital microscopy of cancer cells and MRE experiments
in patient derived tumor explants with tissue-mimicking collagen samples, along with literature …

[HTML][HTML] Bioimpedimetric analysis in conjunction with growth dynamics to differentiate aggressiveness of cancer cells

A Parekh, D Das, S Das, S Dhara, K Biswas… - Scientific reports, 2018 - nature.com
… , death resistance and cellular energy, through bioimpedance … aggressiveness of multiple
cancer cell lines. This further opens avenues for extrapolation of present work to human tumor

Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells

S Yu, MM Murph, Y Lu, S Liu, HS Hall… - … the National Cancer …, 2008 - academic.oup.com
… Based on the sensitivity of ovarian cancer cell proliferation and invasiveness and in vivo tumor
… via LPA2 and LPA3 receptors may play a critical role in the progression of ovarian cancer. …

[HTML][HTML] Melatonin regulates tumor aggressiveness under acidosis condition in breast cancer cell lines

NM Sonehara, JZ Lacerda… - Oncology …, 2019 - spandidos-publications.com
… about the tumor microenvironment and adaptations of the cells beyond the analysis of
molecular characteristics of breast cancer. During the tumorigenesis, cancer cells adapt their …