… and E2F1 transcriptional activity, we sought to identify the immediate downstream targets
of YB-1 by studying three cancer cell lines in vitro. We then used chromatin …

… in the YB-1-promoted cell growth of human cancer cells, and how YB-1 controls expression
of … of CDC6 expression in cancer cells, we evaluated the effect of YB-1 siRNA on cell cycle by …

… We have previously shown that YB-1 is overexpressed in cisplatin-resistant cells and is …
of the YB-1 promoter reveals that several E-boxes may participate in the regulation of YB-1 …

… This opinion was supported by the fact that in stomach and pancreatic cancer cells, inhibition
of YB-1 expression did not change the amount of either P-glycoprotein or MDR1 mRNA …

… Another approach has been to identify the promoters bound by YB-1 in colorectal cancer
or ER-negative breast cancer cells using ChIP (chromatin immunoprecipitation) promoter …

… YB-1 mediates the anti-apoptotic effect on some cancer cells … In HER-2 overexpressing
breast cancer cells, YB-1 inhibition … cell model, apoptosis was noted following inhibition of YB-1 […

… Androgenregulated gene expression is decreased by overexpression of YB-1 and P-gp
in prostate cancer cells. Immunohistochemistry data from tissue microarrays from clinical …

… The YB-1 gene in cancer stem cells was knocked out … YB-1 knockout cancer stem cells were
transfected with a vector expressing YB-1 to rescue YB-1, and then the cell proliferation, cell …

… Initially, we silenced YB-1 with siRNA in a panel of breast cancer cell lines and cell growth
was evaluated 96 hours later … 1A,, representative images of YB-1 knockdown). Seven breast …

… binding protein-1 (YB-1) is associated with cancer aggressiveness, … that YB-1 levels are
elevated in invasive breast cancer cells … of YB-1 in noninvasive breast epithelial cells induced an …