Nanodelivery strategies in cancer chemotherapy: biological rationale and pharmaceutical perspectives

G Mattheolabakis, B Rigas, PP Constantinides - Nanomedicine, 2012 - Taylor & Francis
cancer drug delivery strategies that exploit nanotechnology, providing first an overview of
tumor biology … circumvented limitations in the delivery of cancer therapeutics, related to their …

Biologic rationale of combined radiotherapy and chemotherapy

KK Fu, TL Phillips - Hematology/oncology clinics of North America, 1991 - Elsevier
… This may be one of the causes of failure of randomized trials to demonstrate a significant
beneficial effect of neoadjuvant chemotherapy in head and neck cancer to date. Thus far, with …

Hyperthermia combined with chemotherapybiological rationale, clinical application, and treatment results

R Issels - Oncology Research and Treatment, 1999 - karger.com
… was well tolerated and the clinical results served as the basis to further elucidate the potential
role of WBH as and adjunct to systemic chemotherapy in advanced cancer patients [39]. …

Metronomic chemotherapy: new rationale for new directions

E Pasquier, M Kavallaris, N André - Nature reviews Clinical oncology, 2010 - nature.com
… The potential of metronomic chemotherapy was revealed in … of metronomic chemotherapy
in a variety of human cancers. … of metronomic chemotherapy in adult and pediatric cancer

Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation

GL Gravina, C Festuccia, F Marampon, VM Popov… - Molecular cancer, 2010 - Springer
cancer types. Therefore, as the emerging interest in use of DNMT inhibitors as a potential
chemo… The present article will provide a brief review of the biological significance and rationale

Chemoembolisation in regional cancer chemotherapy: a rationale

N Willmott - Cancer treatment reviews, 1987 - Elsevier
cancer chemotherapy with liposomes, as with cancer chemo… approach is legitimate where
cancer is genuinely a systemic … the apparently systemic nature of cancer "from its inception" (14…

Epidermal Growth Factor Receptor Inhibitors plus Chemotherapy in Non–Small-Cell Lung Cancer: Biologic Rationale for Combination Strategies

DR Gandara, AM Davies, O Gautschi, PC Mack… - Clinical lung cancer, 2007 - Elsevier
… Yet 4 large randomized phase III trials of chemotherapy with … tion studies of chemotherapy
plus monoclonal antibodies … topic and explore the biologic rationale for developing new …

Oral chemotherapy: rationale and future directions.

MD DeMario, MJ Ratain - Journal of clinical oncology, 1998 - ascopubs.org
… for many orally formulated cancer cytotoxics. While these findings are observed for all
classes of oral drugs, the issue is especially critical for cancer chemotherapy, in which a narrow …

Biological rationales and clinical applications of temperature controlled hyperthermia-implications for multimodal cancer treatments

P Schildkopf, OJ Ott, B Frey… - Current medicinal …, 2010 - ingentaconnect.com
… The combination of chemotherapy and … cancers. Table 1 displays exemplarily possible
mechanisms how HT is capable of increasing the efficacy of certain classes of chemotherapeutic

Biological rationale for the design of polymeric anti-cancer nanomedicines

Y Zhou, J Kopeček - Journal of drug targeting, 2013 - Taylor & Francis
… of cancer affect the delivery and interactions of anti-cancer nanomedicines … cancer biological
properties that challenge the currently available anti-cancer treatments, including cancer