Cancer chemotherapy and heterocyclic compounds

M Kidwai, R Venktaramanan… - Current medicinal …, 2002 - ingentaconnect.com
Cancer chemotherapy is now of established value and a … antitumor compounds, heterocyclic
organic compounds have … purine are few classes of heterocycles which showed interesting …

Anti-cancer nitrogen-containing heterocyclic compounds

Z Hosseinzadeh, A Ramazani… - Current Organic …, 2018 - ingentaconnect.com
heterocycles as possible chemotherapy agents for cancer. A simple gleam at FDA databases
shows the structural importance of nitrogen-based heterocycles … words, heterocycles form a …

Cytotoxic effects of chemotherapeutic drugs and heterocyclic compounds at application on the cells of primary culture of neuroepithelium tumors

VA Kulchitsky, VI Potkin, YS Zubenko… - Medicinal …, 2012 - ingentaconnect.com
… If the way of chemotherapeutic treatment of cancer is chosen, … of chemotherapy and heterocyclic
compounds may be one of … (chemotherapy and heterocycles) against malignant tumors. …

Heterocyclic scaffolds: centrality in anticancer drug development

I Ali, M Nadeem Lone, ZA Al-Othman… - Current drug …, 2015 - ingentaconnect.com
… But in general, chemotherapy is used for cancer treatment … compounds inhibit cancer cell
lines via different mechanisms. This article is dedicated to anticancer heterocyclic compounds

Heterocyclic Compounds: Importance in Anticancer Drug Discovery

N Kumar, N Goel - … Current Medicinal Chemistry-Anti-Cancer …, 2022 - ingentaconnect.com
… -cancer drug(s). Herein, we focused on the natural as well as synthetic anti-cancer heterocyclic
compounds. … the mechanism of action of selected heterocyclic anti-cancer compounds. …

Medicinal potential of heterocyclic compounds from diverse natural sources for the management of cancer

M Singh, P Sharma, PK Singh… - Mini Reviews in …, 2020 - ingentaconnect.com
… should be noted that effective cancer chemotherapy often involves the use of combinations
of several agents (so-called combination chemotherapy), and these combination regimens …

Heterocyclic anticancer compounds: recent advances and the paradigm shift towards the use of nanomedicine's tool box

P Martins, J Jesus, S Santos, LR Raposo… - Molecules, 2015 - mdpi.com
… We shall focus on those suitable for cancer therapy while … chemistry, heterocyclic compounds
present themselves as a … -based heterocycles as potential chemotherapeutic cancer drugs, …

A review on the antitumor activity of various nitrogenous-based heterocyclic compounds as NSCLC inhibitors

JC Liu, S Narva, K Zhou… - Mini Reviews in Medicinal …, 2019 - ingentaconnect.com
… Different families of nitrogen-containing heterocycles are currently used in cancer chemotherapy.
1,5-Naphthyridins were discovered as dual ERK2 and Aurora B kinase inhibitors and …

Sulphur Containing Heterocyclic Compounds as Anticancer Agents

B Kaur, G Singh, V Sharma… - … Cancer Agents in Medicinal …, 2023 - ingentaconnect.com
… In cancer chemotherapy, notably for breast cancer, human ABCG2 is known to contribute
to multidrug resistance (MDR). It is a member of the ATP-binding cassette (ABC) transporter …

Hypoxia Mediated Nitro Heterocyclic Drugs in The Radio and Chemothrapy of Cancer

GE Adams, IJ Stratford - Biochemical Pharmacology, 2013 - books.google.com
heterocyclic compounds as hypoxic cell radiation sensitizers correlate in the main (but not
always) with the electron affinities of the compounds… used in cancer chemotherapy are often …