The paradox of autophagy and its implication in cancer etiology and therapy

A Eisenberg-Lerner, A Kimchi - Apoptosis, 2009 - Springer
cancer is complex. This review will discuss the link between autophagy and cancer and will
… different autophagy-inducing drugs that are being used as anti-cancer therapy in the clinic. …

Oxidative stress and liver cancer: etiology and therapeutic targets

Z Wang, Z Li, Y Ye, L Xie, W Li - Oxidative medicine and …, 2016 - Wiley Online Library
… OS and the pathogenesis of liver cancer has been attracting increasing attention. … cancer
from the perspective of cellular and molecular mechanisms and the etiology and therapeutic

Molecular chaperones in the etiology and therapy of cancer

C SŐti, P Csermely - Pathology & Oncology Research, 1998 - Springer
Molecular chaperones are ubiquitous, well-conserved proteins that account for 2–5 % of all
cellular proteins in most cells. The present review summarizes our current knowledge about …

Human reduced folate carrier: translation of basic biology to cancer etiology and therapy

LH Matherly, Z Hou, Y Deng - Cancer and metastasis reviews, 2007 - Springer
This review attempts to provide a comprehensive overview of the biology of the physiologically
and pharmacologically important transport system termed the “reduced folate carrier” (…

Etiology of cancer

BT Hill - Clinical Ophthalmic Oncology: Basic Principles, 2019 - Springer
Therapeutic radiation causes DNA damage and can result in a variety of cancers, including
sarcoma, breast cancer, and hematologic malignancies such as myelodysplastic syndrome …

The etiology of cancer

JF Modiano, M Breen - … Small Animal Clinical Oncology-E-Book, 2012 - books.google.com
… • Figure 1-3 Therapeutic targeting of the hallmarks of cancer. Drugs that interfere with
each of the acquired capabilities necessary for tumor growth and progression have been …

Etiology and management of therapy-related myeloid leukemia

RA Larson - ASH Education Program Book, 2007 - ashpublications.org
therapy-related leukemia among cancer survivors have now been reported on and analyzed.
Although MDS and AML occasionally occur in cancer … , the risk of therapy-related leukemia …

Role of cytochrome P450 genes in breast cancer etiology and treatment: effects on estrogen biosynthesis, metabolism, and response to endocrine therapy

HL Blackburn, DL Ellsworth, CD Shriver… - Cancer Causes & …, 2015 - Springer
… anti-estrogen therapies. Since lifetime estrogen exposure is an established risk factor for
breast cancer, determining the role of CYP genes in breast cancer etiology may provide critical …

Cancer etiology: Agents causally associated with human cancer

H Vainio, J Wilbourn - Pharmacology & toxicology, 1993 - Wiley Online Library
… , but it does not reduce the incidence of cancer. If cancer therapy has had only little impact
on the … cancer from occurring in the first place have stalled. The rates for a number of types of …

Translational control in cancer etiology

D Ruggero - Cold Spring Harbor perspectives in biology, 2013 - cshperspectives.cshlp.org
… to very specific cellular processes that contribute to cancer etiology. In addition, a growing
body … model of cancer formation and offers significant promise for innovative cancer therapies. …