Greasing the wheels of the cancer machine: the role of lipid metabolism in cancer

MT Snaebjornsson, S Janaki-Raman, A Schulze - Cell metabolism, 2020 - cell.com
… membranes but also function as signaling molecules … lipid metabolism in different aspects
of the cancer phenotype and discuss potential strategies by which targeting lipid metabolism

Integration of transcriptomics and machine learning for insights into breast cancer: exploring lipid metabolism and immune interactions

X Chen, J Yi, L Xie, T Liu, B Liu, M Yan - Frontiers in Immunology, 2024 - frontiersin.org
machine learning algorithms into 184 unique combinations to develop a consensus model
for lipid metabolism… ) related to lipid metabolism through analysis of the cancer genome atlas …

[HTML][HTML] New dawn for cancer cell death: emerging role of lipid metabolism

C Zhang, N Zhu, H Li, Y Gong, J Gu, Y Shi, D Liao… - … metabolism, 2022 - Elsevier
… In summary, cancer epigenetics, lipid metabolism, and oncogenic signaling are now widely
considered to be intertwined through a multidirectional, crosstalk regulatory network (Figure 2…

Lipid metabolism and cancer

H Cheng, M Wang, J Su, Y Li, J Long, J Chu, X Wan… - Life, 2022 - mdpi.com
… diversity and chemical complexity, the role of lipids in signaling, … lipid metabolism processes
in tumor treatment, it is particularly important to grasp the basic principles of lipid metabolism

Machine learning survival prediction using tumor lipid metabolism genes for osteosarcoma

S Li, Z Zheng, B Wang - Scientific Reports, 2024 - nature.com
… Firstly, we applied Fisher's exact test to analyze Tumor Lipid Metabolism Genes (TLMGs)
between two subtypes, chosen for their suitability with small, binary datasets to identify genes …

Lipid metabolism-related miRNAs with potential diagnostic roles in prostate cancer

T Zhai, M Dou, Y Ma, H Wang, F Liu, L Zhang… - Lipids in Health and …, 2023 - Springer
… Prostate cancer (PCa), the second most prevalent solid tumor … The effects of lipid metabolism
on tumor growth have been … machine learning methods were employed to develop a lipid

Fat and furious: lipid metabolism in antitumoral therapy response and resistance

M Bacci, N Lorito, A Smiriglia, A Morandi - Trends in cancer, 2021 - cell.com
… Here we focus on the role of lipid metabolic reprogramming … of lipid metabolism such as
lipogenesis, lipid catabolism, and … since deregulated lipid metabolism is a feature of cancer cells …

Lipid metabolism of cancer stem cells

H Liu, Z Zhang, L Song, J Gao… - Oncology Letters, 2022 - spandidos-publications.com
… , exhibit minimal effects on tumor growth inhibition. … to cancer cell survival, such as lipid
metabolism (50). In addition to providing and storing energy as nutrients, lipids also function as …

Machine learning reveals two heterogeneous subtypes to assist immune therapy based on lipid metabolism in lung adenocarcinoma

X Gu, S Wei, Z Li, H Xu - Frontiers in Immunology, 2022 - frontiersin.org
lipid metabolism and tumor immune response in LUAD patients and identified two heterogeneous
subtypes (lipid metabolism … the crosstalk between lipid metabolism and tumor immune …

Construction of machine learning models of lipid metabolism-related long non-coding RNA in lung adenocarcinoma is associated with microenvironmental …

J Xiong, K Xiao, H He, Y Tian - Discover Oncology, 2024 - Springer
… Using the NMF technique, we recruited two groups of lung cancer patients, and we
discovered that the groups’ differences in long non-coding RNA expression patterns related to …