Therapeutic role of alkaloids and alkaloid derivatives in cancer management

K Olofinsan, H Abrahamse, BP George - Molecules, 2023 - mdpi.com
… Despite their structural diversity, quinoline alkaloid derivatives obtained from different
plant sources have been reported to show antineoplastic effects on various cancer cells. Al-…

Alkaloids for cancer prevention and therapy: Current progress and future perspectives

A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
… of synthetic derivatives and pharmacological profiles useful to researchers for the therapeutic
development of alkaloids. Based on the literature survey compiled in this review, alkaloids

Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives

A Evidente, A Kornienko - Phytochemistry Reviews, 2009 - Springer
… Amaryllidaceae species, its extraction methods will be optimized and a prospective
application of this alkaloid or any of its synthetic derivatives in cancer therapy will be pursued. …

Emerging therapeutic efficacy of alkaloids as anticancer agents

SL Pandrangi, SS Chalumuri… - Annals of the Romanian …, 2022 - annalsofrscb.ro
… Here we discuss different types of alkaloids that were … various cancer metabolic pathways
and how various alkaloids … study on derivatives of cancer, it was found that the two derivatives 7…

Therapeutic value of steroidal alkaloids in cancer: Current trends and future perspectives

P Dey, A Kundu, HJ Chakraborty, B Kar… - … journal of cancer, 2019 - Wiley Online Library
… potential of cyclopamine and its derivative in various cancer cell line (in vitro and in vivo)
models. The cyclopamine C-nor-D-homosteroidal alkaloid has been characterized as an …

[HTML][HTML] Phytotherapeutic applications of alkaloids in treating breast cancer

S Rampogu, T Balasubramaniyam, JH Lee - Biomedicine & …, 2022 - Elsevier
… review, 12 alkaloids are reviewed in detail for their potential in treating breast cancer. These
… A combination of berbamine and detoxified pneumolysin derivative ΔA146Ply was used as …

Current perspective of natural alkaloid carbazole and its derivatives as antitumor agents

MS Shaikh, R Karpoormath, N Thapliyal… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
… one such heteroaromatic tricyclic alkaloid is carbazole, which … These alkaloids include
Staurosporine-1, a glycosidic natural … of carbazole alkaloids and their synthetic derivatives from …

Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design

A Evidente, AS Kireev, AR Jenkins, AE Romero… - Planta …, 2009 - thieme-connect.com
… This trend is particularly pronounced in the area of cancer … constituents with potential use
in cancer treatment, plants of … of narcissus oil in cancer management continued in the middle …

Alkaloids and colon cancer: molecular mechanisms and therapeutic implications for cell cycle arrest

H Khan, W Alam, KF Alsharif, M Aschner, S Pervez… - Molecules, 2022 - mdpi.com
… This review aims to shed light on the potential of alkaloids as anti-colon-cancer
alkaloid derivatives with potential therapeutic effect in colon cancer is shown in Table 2. The …

[HTML][HTML] Anticancer alkaloids from trees: Development into drugs

T Isah - Pharmacognosy reviews, 2016 - ncbi.nlm.nih.gov
alkaloids and recent progress in cancer chemotherapy through drugs development.[3,4,5]
The … [152,153] The alkaloid and derivatives showed a multitude of targets in DNA and other …