A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
… in therapeutic miRNA usage are the stability and the delivery … strategies for the development
of therapeutic miRNA delivery systems that includes virus-based delivery, non-viral delivery (…
of therapeutic miRNA delivery systems that includes virus-based delivery, non-viral delivery (…
MicroRNAs and their big therapeutic impacts: delivery strategies for cancer intervention
C Holjencin, A Jakymiw - Cells, 2022 - mdpi.com
… the clinic for cancer treatment that … miRNA delivery platforms for cancer intervention, along
with a discussion of the emergence of peptides as potential carriers for miRNA-based cancer …
with a discussion of the emergence of peptides as potential carriers for miRNA-based cancer …
In vivo delivery of miRNAs for cancer therapy: challenges and strategies
… This review discusses the key challenges to the development of the carriers for miRNA-based
therapy and explores current strategies to systemically deliver miRNAs to cancer without …
therapy and explores current strategies to systemically deliver miRNAs to cancer without …
Nanocarriers for microRNA delivery in cancer medicine
I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
… the application of nanomedicine to cancer therapy. This review covers the different miRNA
therapeutic strategies and delivery challenges for its application in cancer medicine. Current …
therapeutic strategies and delivery challenges for its application in cancer medicine. Current …
Therapeutic microRNA delivery strategies with special emphasis on cancer therapy and tumorigenesis: current trends and future challenges
C Chakraborty, ZH Wen… - Current drug …, 2016 - ingentaconnect.com
… microRNA delivery strategies and also briefly discuss the different miRNA delivery systems
… -based (LNA-based) compounds delivery without any delivery-mediated agent. Finally, we …
… -based (LNA-based) compounds delivery without any delivery-mediated agent. Finally, we …
Targeting microRNAs in cancer: rationale, strategies and challenges
… There are two main strategies to target miRNA expression in cancer. Direct strategies involve
… of an oncogenic miRNA or to substitute for the loss of expression of a tumour suppressor …
… of an oncogenic miRNA or to substitute for the loss of expression of a tumour suppressor …
Progress in microRNA delivery
Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
… strategies of nonviral miRNA delivery systems and provide a perspective on the future of
miRNA… expression can be associated with or even cause diseases in humans, including cancer, …
miRNA… expression can be associated with or even cause diseases in humans, including cancer, …
Therapeutic strategies for miRNA delivery to reduce hepatocellular carcinoma
… The second challenge concerns the efficiency with which miRNA therapeutic agents can
target cancerous cells. How can the specificity in terms of the target tissue and cell type be …
target cancerous cells. How can the specificity in terms of the target tissue and cell type be …
MicroRNA replacement therapy in cancer
H Mollaei, R Safaralizadeh… - Journal of cellular …, 2019 - Wiley Online Library
… The systemic miRNA delivery strategy is a significant progress to overcome the … of miRNA
delivery in vivo and elevate the impact of cancer therapy. Up to now, different systemic delivery …
delivery in vivo and elevate the impact of cancer therapy. Up to now, different systemic delivery …
Challenges identifying efficacious miRNA therapeutics for cancer
M Segal, FJ Slack - Expert opinion on drug discovery, 2020 - Taylor & Francis
… miRNA-based drugs. We also review numerous in vivo delivery strategies and show examples
of the clinical development of miRNA-targeting therapeutics. By focusing on their role in …
of the clinical development of miRNA-targeting therapeutics. By focusing on their role in …
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