Human dendritic cells in cancer

E Kvedaraite, F Ginhoux - Science immunology, 2022 - science.org
… pDC functionality, as pDCs from patients with ovarian cancer were compared in blood, in …
patients with lung cancer, finding no significant difference when compared with cancer patients

Clinical use of dendritic cells for cancer therapy

S Anguille, EL Smits, E Lion, VF van Tendeloo… - The lancet …, 2014 - thelancet.com
dendritic cells have been used in clinical trials as cellular mediators for therapeutic
vaccination of patients with cancer… of dendritic cell vaccination with other cancer therapies. …

The use of dendritic cells in cancer therapy

M Jefford, E Maraskovsky, J Cebon, ID Davis - The Lancet Oncology, 2001 - thelancet.com
… -phase clinical trials of dendritic cells for the treatment of cancer. These … This paper reviews
the biology of dendritic cells and their … patients of a vaccine with peptide-pulsed dendritic cells

[HTML][HTML] Dendritic cells in the cancer microenvironment

Y Ma, GV Shurin, Z Peiyuan, MR Shurin - Journal of Cancer, 2013 - ncbi.nlm.nih.gov
… of immune cell differentiation and function makes this unique environment even more intricate
and variable. Dendritic cells (DCs) represent a special group of cells that display different …

Cancer immunotherapy by dendritic cells

CJM Melief - Immunity, 2008 - cell.com
… -driven immunosuppressive leukocyte infiltrates, mainly myeloid-derived suppressor cells,
tumor-associated macrophages, and immature dendritic cells (DCs). In addition, many tumors …

The role of dendritic cells in cancer

M Hansen, MH Andersen - Seminars in immunopathology, 2017 - Springer
… have been shown to require nitric oxide synthase-2 (NOS2/iNOS), which is abundant in,
for example, ascites from ovarian cancer patients [70]. The presence of PGE 2 during in vitro …

Dendritic cells in cancer immunotherapy

L Fong, EG Engleman - Annual review of immunology, 2000 - annualreviews.org
… in a manner that rendersthem immunogenic in patients with cancer. However, recent insights
into therole of dendritic cells (DC) as the pivotal antigen-presenting cells (APC) thatinitiate …

Decreased antigen presentation by dendritic cells in patients with breast cancer.

DI Gabrilovich, J Corak, IF Ciernik, D Kavanaugh… - … Association for Cancer …, 1997 - AACR
… 7 Improved stimulation of influenza virus-specific CTLs by breast cancer patient DCs … when
T cells from patients were stimulated … capacity of the T cells from cancer patients, we tested …

Dendritic cells injected via different routes induce immunity in cancer patients

L Fong, D Brockstedt, C Benike, L Wu… - The Journal of …, 2001 - journals.aai.org
Dendritic cells (DC) represent potent APCs that are capable of generating tumor-specific
immunity. We performed a pilot clinical trial using Ag-pulsed DC as a tumor vaccine. Twenty-…

Clinical significance of defective dendritic cell differentiation in cancer

B Almand, JR Resser, B Lindman, S Nadaf… - Clinical Cancer …, 2000 - AACR
… Surgical removal of the tumor had a great impact on the presence of immature cells in
cancer patients. We compared the proportion of immature cells in five cancer patients. All …