Biomolecular condensates and their links to cancer progression

D Cai, Z Liu, J Lippincott-Schwartz - Trends in biochemical sciences, 2021 - cell.com
… are also intricately linked to cancer formation and progression. We review the most recent
… of biomolecular condensates to different hallmarks of cancer formation and progression. We …

Biomolecular condensates in neurodegeneration and cancer

S Spannl, M Tereshchenko, GJ Mastromarco, SJ Ihn… - Traffic, 2019 - Wiley Online Library
… We continue to learn various ways that biomolecular condensates can function in vitro and
in cells, yet the functional roles of many cellular condensates in cell physiology remain not …

Biomolecular condensates in cancer biology

HI Suzuki, K Onimaru - Cancer Science, 2022 - Wiley Online Library
… the possibility of therapeutic targeting of condensates. This review summarizes recent …
and biomolecular condensate models, multiple scenarios of condensate alterations in cancers, …

Targeting biomolecular condensation and protein aggregation against cancer

JL Silva, D Foguel, VF Ferreira, TCRG Vieira… - Chemical …, 2023 - ACS Publications
… diseases and cancer. This review thoroughly examines the dual nature of biomolecular
condensates, spotlighting their role in cancer, particularly concerning the p53 tumor suppressor. …

Biomolecular condensates and cancer

A Boija, IA Klein, RA Young - Cancer cell, 2021 - cell.com
… dysregulation in cancer. Here we summarize key features of biomolecular condensates, note
… evidence that the pharmacodynamics of cancer therapeutics can be greatly influenced by …

Biomolecular condensation: a new phase in cancer research

AK Chakravarty, DJ McGrail, TM Lozanoski, BS Dunn… - Cancer discovery, 2022 - AACR
cancers. A string of recent articles have begun to delineate a potential role for biomolecular
condensates in … of these condensates. In this context, DNA translocations that are common in …

[HTML][HTML] An Insight into Cancer from Biomolecular Condensates

Q Maqsood, A Sumrin, MZ Saleem… - Cancer Screening …, 2023 - xiahepublishing.com
biomolecular condensates instead … cancer through biomolecular condensates and their
role in therapeutics such as association of condensates production and pathogenesis in cancer. …

A framework for understanding the functions of biomolecular condensates across scales

AS Lyon, WB Peeples, MK Rosen - Nature Reviews Molecular Cell …, 2021 - nature.com
… and cellular functions of biomolecular condensates from the recent … of the widespread roles
of condensates in cell biology. … to diseases including neurodegeneration and cancer 22,23 . …

To condense or not to condense: Wnt regulation by centrosome-nucleated biomolecular condensates

M Peifer - Proceedings of the National Academy of …, 2022 - National Acad Sciences
cancer is the third leading cause of cancer deaths worldwide, and, thus, understanding genetic
changes driving cancer development and progression … cloned the tumor suppressor gene …

Onco-condensates: formation, multi-component organization, and biological functions

C Xu, A Kim, JM Corbin, GG Wang - Trends in cancer, 2023 - cell.com
Cancer frequently coopts biomolecular condensation mechanisms to promote survival and/or
proliferation. Onco-condensates… , or to suppress a tumor-suppressive pathway, thereby …