… Our focus in this review is to summarize the known data on the role of IL-1 in tumor
progression and metastasis and the use of IL-1 inhibition as a novel therapeutic approach in the …

… IL-1β and mutated-KRAS seems to increase cancer progression and drug resistance. …
in human breast cancer cells, thus contributing to cancer progression [146]. In colon cancer, …

… .2, 6 IL-1 is a prototypic inflammatory … IL-1 and its regulation play a pivotal role in cancer-related
inflammation. Here, we will review how IL-1 affects various aspects of tumor progression …

… , IL-1, TNFα, and TLR can promote cancer progression through NF-κB or AP-1. In this review…
of IL-1α and IL-1β in breast cancer (BCa) progression and therapeutic resistance, and state …

… cancer [1], [2] and while exciting preclinical and clinical data have emerged implicating
inflammation in the development and progression of certain cancers, … and types of cancer is still in …

… of the IL-1 family in the human breast cancer microenvironment and suggest a role for the
IL-1 family in breast cancer progression based on the correlation of IL-1 family members with …

… Background: Inflammation is known to promote tumor formation and progression; however,
we found a natural anti-inflammatory factor, interleukin (IL)-1 receptor antagonist (IL1RN), in …

… release of proinflammatory cytokines, such as interleukin (IL)-1β. There is … cancer progression.
This short review proposes the possibility of using IL-1β as a potential cancer progression …

… and has resulted in improved survival in colorectal and lung cancer patients and progression-free
survival in breast cancer patients. [73] Inhibition of VEGF receptor signaling by tyrosine …

… The interleukin-1 (IL-1) family is one of … in cancer has been well established in the past
decades. This review sets out to give an overview of the role of each IL-1 family member in cancer …