… in solid tumors is itself a complex pathologic process, with contributions from classic immune
cells as well as poorly characterized, cancer-associated fibroblasts and the epithelial tumor …

… cancer risk and tumorigenesis. Here, we outline basic principles of innate immune cell
functions in inflammation and discuss how these functions converge upon cancer development. …

… it is associated with breast cancer risk. Together, our findings suggest that women’s circulating
immune cell profiles may change in the years leading up to a breast cancer diagnosis. …

… Mechanisms responsible for immune cell dysfunction in patients with cancer are numerous
and varied, as illustrated in Fig. 1. In addition to a wide variety of soluble immunosuppressive …

… counts of immune cell and cancer risks. When relative counts of immune cell types were taken
… counts of FOXP3 + regulatory T cells (Tregs) and lung cancer risk, and significant inverse …

… factors and immune cells may be a key mechanism of how exercise counteracts cancer in
… alterations in the immune system may contribute to the increased cancer risk in the older …

… STAT3 is not directly activated by oncogenic mutations, it exerts critical oncogenic functions
in both cancer and immune cells within the microenvironment [34]. More recently, mouse …

… Innate immune cells directly potentiate cancer risk through the diversity of bioactive
mediators they secrete and/or deliver to neoplastic tissue microenvironments. Leukocytes are …

… These immune cells and the cellular factors produced from them, including both … in promoting
or discouraging cancer development, and their ultimate role in cancer progression may rely …

… tumour and immune cells in cancer microenvironment, it is challenging to define the role
of immune cell types, cytokines or growth factors in promoting or containing cancer. Thus, …