[HTML][HTML] Cost-effectiveness and comparative effectiveness of cancer risk management strategies in BRCA1/2 mutation carriers: a systematic review
… Eligible studies modeled the impact of a cancer risk management intervention in BRCA
carriers on life expectancy (LE), cancer incidence, or quality-adjusted life years (QALYs), with or …
carriers on life expectancy (LE), cancer incidence, or quality-adjusted life years (QALYs), with or …
… Providers, Family Members, and Other Mutation Carriers in the Cancer Risk Management Decision-Making Process of BRCA1 and BRCA2 Mutation Carriers
… cancer risk and decision-making, we excluded women with a previous or current ovarian
cancer … right, and normalization of cancer risk management to participants during the decision-…
cancer … right, and normalization of cancer risk management to participants during the decision-…
[HTML][HTML] Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers
AW Kurian, BM Sigal, SK Plevritis - Journal of Clinical Oncology, 2010 - ncbi.nlm.nih.gov
… cancer risks for BRCA1 and BRCA2 mutation carriers from meta-analyses. Since approximately
30% of BRCA1/2 mutation carriers … that reported breast cancer incidence 2 incorporates …
30% of BRCA1/2 mutation carriers … that reported breast cancer incidence 2 incorporates …
Risk reduction and survival benefit of prophylactic surgery in BRCA mutation carriers, a systematic review
KK Ludwig, J Neuner, A Butler, JL Geurts… - The American Journal of …, 2016 - Elsevier
… Primary studies of BRCA mutation carriers who have undergone BRRM in … risk reduction
in breast cancer incidence. The risk of breast cancer after BRRM is less than 3%, and the risk …
in breast cancer incidence. The risk of breast cancer after BRRM is less than 3%, and the risk …
Modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: a systematic review and meta-analysis
TM Friebel, SM Domchek… - … of the National Cancer …, 2014 - academic.oup.com
… role that risk modifiers may contribute to the risk assessment … regarding cancer risk modifiers
in BRCA1/2 mutation carriers … inform the use of risk modifiers in cancer risk counseling, as …
in BRCA1/2 mutation carriers … inform the use of risk modifiers in cancer risk counseling, as …
[HTML][HTML] Clinical application of multigene panels: challenges of next-generation counseling and cancer risk management
TP Slavin, M Niell-Swiller, I Solomon, B Nehoray… - Frontiers in …, 2015 - frontiersin.org
… cancer risk (1), genetic cancer risk assessment (GCRA) enables informed choices about
cancer … The largest study of PALB2 mutation carriers to date indicated that the cumulative risk of …
cancer … The largest study of PALB2 mutation carriers to date indicated that the cumulative risk of …
Cancer risk reduction and reproductive concerns in female BRCA1/2 mutation carriers
… management of elevated cancer risk, we evaluated the decisions of BRCA1/2 mutation carriers
… high-risk women’s preferences about cancer risk management and reproductive options …
… high-risk women’s preferences about cancer risk management and reproductive options …
[HTML][HTML] “There should be one spot that you can go:” BRCA mutation carriers' perspectives on cancer risk management and a hereditary cancer registry
… Specifically, this paper focuses on BRCA mutation carriers’ perspectives on (and interest
in) an inherited cancer registry and explores carriers’ experiences with the current care model …
in) an inherited cancer registry and explores carriers’ experiences with the current care model …
Risk management options elected by women after testing positive for a BRCA mutation
C Garcia, J Wendt, L Lyon, J Jones, RD Littell… - Gynecologic …, 2014 - Elsevier
… To assess the uptake of risk-reducing options for the management of ovarian and breast
cancer risk in BRCA mutation carriers in a large community based integrated health system in …
cancer risk in BRCA mutation carriers in a large community based integrated health system in …
Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: revisiting the evidence for risk reduction
…, Hereditary Breast and Ovarian Cancer … - … the National Cancer …, 2015 - academic.oup.com
… Using a simple, more valid method of analysis, we found no evidence for first BC risk
reduction after RRSO in BRCA1/2 mutation carriers. We suggest that counselors, clinicians, and …
reduction after RRSO in BRCA1/2 mutation carriers. We suggest that counselors, clinicians, and …
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