… different signalling in cancer stem cells requires in … cancer stem cells historical background
and to provide a brief review of the new therapeutic strategies for targeting cancer stem cells…

… Cancer stem cells (CSC) are a small subset of tumor cells with the capability to influence
self… A number of surface markers for liver cancer stem cell (LCSC) subpopulations (EpCAM, …

… cancer stem cell (CSC). Although it was initially believed that only a rare population of stem
cells … malignancy, a recent work has shown that these cells may not be as rare as thought first…

… SOX2 regulates tumour maintenance and cancer-cell functions in primary mouse skin tumours,
we induced Sox2 deletion in pre-existing tumour cells and performed microarray and qRT…

… through cell division. There is growing recognition of the importance of cancer stem cells (…
, leading to the production of a spectrum of cancer cell-types that comprise the bulk tumor. …

… of cancer stem cells (CSCs). CSCs are a relatively rare population of cancer cells capable
of … understanding of the function of signaling pathways in both normal stem cells and CSCs. …

… regulating CSC functions Cancer stem cells (CSCs) differ from the normal stem cells in their
… repopulating a tumor after treatment resulting in cancer relapse [35,36]. Similarly to normal …

… cancer, in clinical practice. It has been suggested that tumor tissue contains a type of stem cell
referred to as a cancer stem cell… , thus proving that the cap cells function as a true stem cell …

… maintenance of normal tissue stem cell hierarchies. Similarly, … of self-renewing cancer stem
cells (CSCs) sustains the long-… a tumor cell with the TME influences the function of that cell, …

… biology of progenitor and adult stem cells in many organs like the … signaling also plays an
essential role in cancer stem cells [4]. … have been linked to stem cell functions, for instance R-…