Cancer stem cells: markers or biomarkers?

WA Woodward, EP Sulman - Cancer and metastasis reviews, 2008 - Springer
… Similarly, stem cells in solid organs also can be identified using cell surface markers. In
addition, solid … Of particular concern, these tumor-initiating cells (termed cancer stem cells when …

Emerging functional markers for cancer stem cell-based therapies: Understanding signaling networks for targeting metastasis

S Marquardt, M Solanki, A Spitschak, J Vera… - Seminars in cancer …, 2018 - Elsevier
Metastasis is one of the most challenging issues in cancer patient management, and effective
therapies to specifically target disease progression are missing, emphasizing the urgent …

More than markers: biological significance of cancer stem cell-defining molecules

SB Keysar, A Jimeno - Molecular cancer therapeutics, 2010 - AACR
… array of solid tumors, labeled cancer stem cells (CSC) or … Recent data have shown that these
markers are inducible by … also the functionality of these markers. The involvement of CD44 …

Molecular mechanisms underlying the functions of cellular markers associated with the phenotype of cancer stem cells

E Alvarado-Ortiz, MÁ Sarabia-Sánchez… - … stem cell research & …, 2019 - ingentaconnect.com
… is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer … Breast
cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct …

[HTML][HTML] Cancer stem cell surface markers on normal stem cells

WT Kim, CJ Ryu - BMB reports, 2017 - ncbi.nlm.nih.gov
… tumors, more functional markers are needed. To isolate functional CSCs, there is a need to
search for more specific surface markers, or use multiple surface markers in combination. We …

Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?

C Fillmore, C Kuperwasser - Breast cancer research, 2007 - Springer
… mass has shifted the focus of cancer research. However, there is … markers that distinguish
cancer stem cells in the breast. As such, understanding whether CD44 + /CD24 - breast cancer

Cancer stem cell markers in common cancers–therapeutic implications

T Klonisch, E Wiechec, S Hombach-Klonisch… - Trends in molecular …, 2008 - cell.com
… in the cancer stem cell (CSC) field have provided cause for optimism for the development of
more reliable cancer … for monitoring the progress of cancer therapy and for evaluating new …

[HTML][HTML] Stem cells, colorectal cancer and cancer stem cell markers correlations

I Cherciu, A Bărbălan, D Pirici… - Current health …, 2014 - ncbi.nlm.nih.gov
… will cause the changeover to cancerous stem cells (CSC) … This review will focus on the
colorectal cancer stem cell (CR-CSCs) … cancer stem cells (CR-CSCs), colorectal neoplasms stem

Embryonic stem cell markers expression in cancers

M Schoenhals, A Kassambara, J De Vos… - Biochemical and …, 2009 - Elsevier
cancer stem cells arise and self-renew. The overexpression of Oct3/4, Sox2, Klf4 and/or c-Myc
could contribute to the pathological self-renewal characteristics of cancer stemfunction as …

Cancer stem cells—perspectives on current status and future directions: AACR Workshop on cancer stem cells

MF Clarke, JE Dick, PB Dirks, CJ Eaves… - Cancer research, 2006 - AACR
… cells as cancer stem cells without confirmation by functionalfunctionally link any marker to
stem cell identity. Although the isolation of markers correlated with stem cells can aide in stem