… Stem cells are defined by their intrinsic capacity to self-renew and differentiate. Cancer stem
cells … The canonical Wnt/β-catenin signaling pathway plays a central role in modulating the …

… We have previously postulated that cancer stemness may be conferred by specific levels
of β-catenin activation in colorectal cancer (Brabletz et al, 2005a; Fodde and Brabletz, 2007). …

… Wnt/β-catenin signaling and how the pathway regulates normal differentiation of stem cells in
the … cancer stem cells and the potential therapeutic implications of regulating Wnt signaling. …

… stemness of the cancer stem cells. However, the underlying mechanisms about mortalin
maintaining the stemness of breast cancer stem cells (… mortalin in breast cancer was associated …

… cancer is the recurrence induced by breast cancer stem cells (CSCs). Understanding the role
and molecular mechanism of specific molecules in breast cancer stem cells … breast cancer. …

… the Wnt/β-catenin inhibitor ICG-001 partially reversed EMT and attenuated cancer stemness.
Our … from M2-TAMs promote EMT and cancer stemness cells via the Wnt/β-catenin pathway. …

… TM4SF1 drives EMT and cancer stemness in CRC through Wnt/β-catenin signalling To
investigate the molecular mechanism of TM4SF1 in EMT and cancer stemness, we performed …

… been verified in Chinese patients with triple-negative breast cancer. Cancer stem cells (CSC)
play an important role in the development and metastasis of breast cancer [18]–[20]. Breast …

… We now provide evidence that differential requirements for β-catenin signalling in cancer
versus normal stem cells exist in skin, which could be exploited for future therapy. …

… depending on the β-catenin-TCF/… β), FGF (fibroblast growth factor), Hedgehog, Notch and
YAP signaling cascades in the tumor microenvironment and affect cancer stem cells, cancer…