New approaches to molecular cancer therapeutics

I Collins, P Workman - Nature chemical biology, 2006 - nature.com
… We assess the progress and current challenges of cancer drug discovery, and finally we …
of cancer therapeutics. The molecular basis of cancer: drugging the cancer genome …

Nanomedicines as cancer therapeutics: current status

S Akhter, I Ahmad, MZ Ahmad… - Current cancer drug …, 2013 - ingentaconnect.com
… medicines are potential toxicity … cancer therapeutics. This review highlights
nanopharmaceuticals that have been investigated in oncology for various applications (diagnosis, …

Cancer therapeutics-opportunities, challenges and advances in drug delivery

D Kakde, D Jain, V Shrivastava, R Kakde… - Journal of Applied …, 2011 - japsonline.com
… characteristics of the cancer that provide opportunities for drug delivery carriers to target cancer.
These … The newer approaches to cancer treatment not only supplement the conventional …

Cyclic depsipeptides as potential cancer therapeutics

J Kitagaki, G Shi, S Miyauchi, S Murakami… - … -cancer drugs, 2015 - journals.lww.com
… study indicate that cyclic depsipeptides could be a rich source of new cancer therapeutics. …
human esophageal squamous cancer cell lines showed that the drug upregulated 11 genes …

mTOR kinase inhibitors as potential cancer therapeutic drugs

SY Sun - Cancer letters, 2013 - Elsevier
… The mTOR axis is often activated in many types of cancer and thus has become an attractive
cancer therapeutic target. The modest clinical anticancer activity of conventional mTOR …

Antibody targeted drugs as cancer therapeutics

D Schrama, RA Reisfeld, JC Becker - Nature reviews Drug discovery, 2006 - nature.com
… of cancer therapeutics is the targeting of drugs to the tumor by using the specificity of antibodies.
All different kinds of drug … In addition to being effective cancer therapeutics on their own, …

Emergence of cardiac glycosides as potential drugs: Current and future scope for cancer therapeutics

R Kumavath, S Paul, H Pavithran, MK Paul, P Ghosh… - Biomolecules, 2021 - mdpi.com
… , we present our current understanding of the targeted therapeutic potential of transcription
factors and the role of CGs in modulating these proteins in cancer as depicted in Figure 2. …

Novel delivery approaches for cancer therapeutics

AK Mitra, V Agrahari, A Mandal, K Cholkar… - Journal of controlled …, 2015 - Elsevier
… of novel cancer treatment strategies. In contrast to conventional cancer therapeutics, novel
… release, intracellular drug targeting, gene delivery, cancer stem cell therapy, magnetic …

Nanocarriers in advanced drug targeting: setting novel paradigm in cancer therapeutics

MH Akhter, M Rizwanullah, J Ahmad… - Artificial cells …, 2018 - Taylor & Francis
… single drug treatment module due to higher internalization of chemotherapeutics in the cancer
… The cancer therapeutics involves different methodologies of delivering active moiety to the …

Giving drugs a second chance: overcoming regulatory and financial hurdles in repurposing approved drugs as cancer therapeutics

JJ Hernandez, M Pryszlak, L Smith, C Yanchus… - Frontiers in …, 2017 - frontiersin.org
… In fact, this strategy of using existing therapeutics for new indications has demonstrated … III
clinical trials as a cancer therapeutic (1). Ideal candidates for drug repurposing are entities that …