[HTML][HTML] Cell signaling and cancer

GS Martin - Cancer cell, 2003 - cell.com
… as possible targets for cancer therapy are signaling proteins that are components of these
… of cellular signaling networks has major implications for our understanding of tumor cell

Bacterial cupredoxin azurin hijacks cellular signaling networks: protein–protein interactions and cancer therapy

M Gao, J Zhou, Z Su, Y Huang - Protein Science, 2017 - Wiley Online Library
… to interfere in different cellular signaling pathways. So far, two segments have been identified
responsible for interactions between azurin and the signaling targets. The central segment …

Apoptotic cell signaling in cancer progression and therapy

J Plati, O Bucur, R Khosravi-Far - Integrative biology, 2011 - academic.oup.com
… Notably, various upstream signaling pathways often impinge on the same few central … in
cancer cells. We will also briefly discuss the development of some promising cancer treatment

Intracellular signal transduction pathway proteins as targets for cancer therapy

AA Adjei, M Hidalgo - Journal of Clinical Oncology, 2005 - ascopubs.org
… Thus, it represents an attractive target for cancer therapy. This review will summarize current
knowledge of selected intracellular signaling networks and their role in cancer therapy. The …

Cancer stem cell signaling pathways

WH Matsui - Medicine, 2016 - journals.lww.com
… of the function of signaling pathways in both … pathways may promote resistance to cancer
therapeutics through maintenance of the CSC population; PI3K and Notch signaling pathways

Key cancer cell signal transduction pathways as therapeutic targets

R Bianco, D Melisi, F Ciardiello, G Tortora - European journal of cancer, 2006 - Elsevier
… attractive targets for cancer therapy. This review will summarize current knowledge of key
signal transduction pathways, that are altered in cancer cells, as therapeutic targets for novel …

Regulation of cell signaling pathways by berberine in different cancers: searching for missing pieces of an incomplete jig-saw puzzle for an effective cancer therapy

AA Farooqi, MZ Qureshi, S Khalid, R Attar, C Martinelli… - Cancers, 2019 - mdpi.com
… our knowledge related to the multifaceted nature of cancer and strategies to therapeutically
target deregulated signaling pathways in different cancers. In this review, we have set the …

Modeling signaling networks to advance new cancer therapies

J Saez-Rodriguez, A MacNamara… - Annual review of …, 2015 - annualreviews.org
therapies for diseases such as cancer. Using the MAPK (mitogen-activated protein kinase)
and PI3K (class I phosphoinositide-3′ kinase) pathways as case studies of cellular signaling

[HTML][HTML] Targeting cancer by binding iron: Dissecting cellular signaling pathways

GYL Lui, Z Kovacevic, V Richardson, AM Merlot… - Oncotarget, 2015 - ncbi.nlm.nih.gov
treatment of cancer. Herein, we review recent research on the targeting of iron for cancer
therapy, … not only target cellular iron, but also multiple signaling pathways that are implicated in …

Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy

JD Wulfkuhle, R Speer, M Pierobon… - Journal of proteome …, 2008 - ACS Publications
… Phosphoprotein driven cellular signaling events represent most of the new molecular
targets for cancer treatment. Application of reverse-phase protein microarray technology for the …