… investigated to act as cancer chemotherapeutics. The primary … cancer, and further discuss
the underlying mechanisms of anti-tumor activities of HDAC inhibitors and clinical implications. …

Extensive cancer research in the past few decades has identified the existence of a rare
subpopulation of stem cells in the grove of cancer cells. These cells are known as the cancer …

… greatest clinical implication evolving around the CSC hypothesis is that one may need to
develop targeted treatment regimes against the unique CSC population for the cure of cancer [7…

… an addition to therapeutic strategies recruited for managing cancer. Considering available
… strategies for combating cancer. In this review, the possible clinical applications of Notch1 …

… cancer therapy. The selection of mAbs for specific targeting and harnessing the therapeutic
… precision acting only on cancer cells, increasing the therapeutic index while minimizing the …

… has dramatically changed the view of cancer treatment, and numerous novel therapies have
been developed and approved by the FDA. However, cumulative clinical data point at very …

… that render complete cancer genome characterization … and clinical insights gleaned from
systematic cancer genome characterization. We also discuss how the convergence of cancer …

Anorexia and reduced food intake are important issues in the management of patients with
cancer because they contribute to the development of malnutrition, increase morbidity and …

… Precision medicine is becoming considerably critical in colorectal cancer therapy. … on
addressing the clinical implication of CRC heterogeneity in anti-EGFR therapies, exploring the …

… Angiogenesis has long been considered an important target for cancer therapy. Initial efforts
have primarily focused on targeting of endothelial and tumor-derived vascular endothelial …