… biological importance of copper and copper homeostasis in … of copper dysregulation in
cancer, and the recent therapeutic … These copper coordination complexes are discussed in the …

… Human clinical trials continue to evaluate the therapeutic efficacy of copper complexes as …
the main copper complexes that are currently being repurposed for cancer therapy and detail …

… agents (see Table 1 for list of complexes and compounds that can complex copper and their
… Cu-based cancer treated appears to be a potentially important area of future cancer therapy …

… We further tested biological effects of the CQ-copper complex in human prostate cancer …
death occurred in both prostate cancer cell lines treated with CQ-copper complex, but not with …

… complexes. Recent research has also investigated the potential of copper complexes in
cancer therapy… potential applications of copper complexes in chemodynamic therapy are vast, …

… The anti-angiogenesis effects, as well as the potential use of proteasome inhibitors in
cancer therapies, have been extensively reviewed [45, 46]. It has been found that, like other …

… about the use of gold, silver and copper complexes as antitumor agents, highlighting their
… implicated in cancer onset and progression. The identification of lead complexes targeting …

… copper complexes in a concise perspective, with a focus on connections between the UPS
and cancer… section, we will highlight several well-studied copper complexes in tumor therapy. …

… of various non platinum metal complexes and metal-chelating … in tumor cells and their
applications in cancer therapy. … cancer cells possess trace to undetectable levels of copper [108, …

… In addition to platinum-based drugs, complexes of several other metals, including copper (…
vivo in cancer therapy (6–9). The disulfiram (DSF)-Cu and clioquinol (CQ)-Cu complexes are …