Harnessing cytokines and chemokines for cancer therapy

DJ Propper, FR Balkwill - Nature reviews Clinical oncology, 2022 - nature.com
… , we review both cytokine and anti-cytokine approaches to cancer therapy herein. Clinical
trials of cytokine therapy Strong evidence indicates that some cytokines, especially those …

Therapeutic potential of cytokine and chemokine antagonists in cancer therapy

L Yan, GM Anderson, M DeWitte, MT Nakada - European journal of cancer, 2006 - Elsevier
… , may provide highly efficacious therapeutic regimens for the treatment of malignancies.
This article reviews anti-cytokine and anti-chemokine therapies being pursued in cancer, and …

Chemokines and cancer: new immune checkpoints for cancer therapy

N Karin - Current Opinion in Immunology, 2018 - Elsevier
… Likewise we have shown that the half-life of a cytokine (IL-31) could be extended via this
technology [32]. Here we are suggesting that CXCL10 that enhances anti-tumor immunity could …

The use of cytokines and chemokines in the cancer immunotherapy

A Amedei, D Prisco, MM D'Elios - … patents on anti-cancer drug …, 2013 - ingentaconnect.com
cancer types. The aim of this paper is to analyze the recent patents and scientific reviews on
the major cytokine/chemokine pathways involved in cancercancer therapeutic applications. …

Chemokines in cancer

AP Vicari, C Caux - Cytokine & growth factor reviews, 2002 - Elsevier
chemokines promote tumor development. On the other hand, chemokines could be used
to the benefit of cancer … However, chemokine-mediated recruitment of immature DC within …

Chemokines and chemokine receptors: A new strategy for breast cancer therapy

H Liu, Z Yang, W Lu, Z Chen, L Chen, S Han… - Cancer …, 2020 - Wiley Online Library
… factors in increasing the mortality of breast cancer patients. The existing treatment methods
… breast cancer to improve the therapeutic effect. Chemokine is a kind of chemotactic cytokine, …

Association of cytokines and chemokines in pathogenesis of breast cancer

J King, H Mir, S Singh - Progress in Molecular Biology and translational …, 2017 - Elsevier
… for cancer cells. The dynamics of cross talk between immune system … cancer cells mediated
by cytokines and chemokines changes during cancer initiation, progression, and therapeutic

Chemokines driven ovarian cancer progression, metastasis and chemoresistance: Potential pharmacological targets for cancer therapy

S Bose, P Saha, B Chatterjee, AK Srivastava - Seminars in Cancer Biology, 2022 - Elsevier
… The cells present in TME secrete various inflammatory mediators including chemokines
and cytokines, which regulate the tumor progression and metastasis. This review article …

[HTML][HTML] Role of cytokines and chemokines in angiogenesis in a tumor context

M Geindreau, M Bruchard, F Vegran - Cancers, 2022 - mdpi.com
… a hallmark of cancer and has been the target of new therapies this … We will then discuss how
the cytokines and chemokines … the therapeutic arsenal targeting angiogenesis in cancer and …

Chemokines and cytokines: Axis and allies in prostate cancer pathogenesis

M Mughees, JB Kaushal, G Sharma, S Wajid… - Seminars in cancer …, 2022 - Elsevier
Chemokines are recognized as the major contributor … cancer therapies. The tumor
microenvironment (TME) is enriched with chemokines and cytokines and plays a pivotal role in …