Thioredoxin reductase as a novel molecular target for cancer therapy
… pathways, may represent a potential molecular target candidate in response to agents …
identify a molecular target. Based on these results we believe TR is a potential molecular target …
identify a molecular target. Based on these results we believe TR is a potential molecular target …
Molecular targets and cancer therapeutics: discovery, development and clinical validation
BA Teicher - Drug Resistance Updates, 2000 - Elsevier
… The cyclin-dependent kinases remain a major focus as molecular targets with agents such
as flavopiridol which is in Phase II clinical trial and UCN-01 which is in Phase I clinical trial …
as flavopiridol which is in Phase II clinical trial and UCN-01 which is in Phase I clinical trial …
Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway
J Polivka Jr, F Janku - Pharmacology & therapeutics, 2014 - Elsevier
… trials for many different types of cancer. This review focuses on … molecular targets for cancer
therapy found in key pathway members and their corresponding experimental therapeutic …
therapy found in key pathway members and their corresponding experimental therapeutic …
NFκB signaling in carcinogenesis and as a potential molecular target for cancer therapy
HM Shen, V Tergaonkar - Apoptosis, 2009 - Springer
… molecular link bridging inflammation and cancer. As a result, NFκB becomes an ideal molecular
target in controlling cancer … their cancer therapeutic and chemo-preventive effects [16]. …
target in controlling cancer … their cancer therapeutic and chemo-preventive effects [16]. …
Vimentin in cancer and its potential as a molecular target for cancer therapy
A Satelli, S Li - Cellular and molecular life sciences, 2011 - Springer
… approaches for the development of therapeutic agents. This review … cancer and suggests
some directions toward future cancer therapy utilizing vimentin as a potential molecular target…
some directions toward future cancer therapy utilizing vimentin as a potential molecular target…
Integrins: molecular targets in cancer therapy
GC Tucker - Current oncology reports, 2006 - Springer
… Surprisingly, despite the broad theoretical impact of such molecules on integrin function,
and thus on pathology, the clear identification of discrete clinical niches for their use remains to …
and thus on pathology, the clear identification of discrete clinical niches for their use remains to …
Screening of potential molecular targets for colorectal cancer therapy
K Honma, I Takemasa, R Matoba… - … journal of general …, 2009 - Taylor & Francis
… a molecular targeted therapy for cancer. In this paper, we focused on apoptosis induction to
identify molecular targets for colorectal cancer therapy… in human colorectal cancer tissues for …
identify molecular targets for colorectal cancer therapy… in human colorectal cancer tissues for …
NF‐κB as a potential molecular target for cancer therapy
CH Lee, YT Jeon, SH Kim, YS Song - Biofactors, 2007 - Wiley Online Library
… cancer therapy strategy. In addition, recent studies have shown that NF‐κB can also play a
tumor … in carcinogenesis and the therapeutic potential of targeting NF‐κB in cancer therapy. …
tumor … in carcinogenesis and the therapeutic potential of targeting NF‐κB in cancer therapy. …
Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds
… –target interactions, particularly for older molecules, we highlight opportunities for repurposing
compounds as cancer therapeutics, … relevant affinities for new targets. Ideal candidates for …
compounds as cancer therapeutics, … relevant affinities for new targets. Ideal candidates for …
Notch signaling: emerging molecular targets for cancer therapy
L Yin, OC Velazquez, ZJ Liu - Biochemical pharmacology, 2010 - Elsevier
… It, therefore, places Notch signaling as a potential target for cancer therapeutics. An … information
for the identification of molecular targets to design effective therapeutic strategies (Fig. 3). …
for the identification of molecular targets to design effective therapeutic strategies (Fig. 3). …
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