Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
… -based anticancer therapies, including therapeutic applications of miRNAs, challenges of …
the delivery obstacles, and the development of miRNA delivery systems for cancer therapy. …

In vivo delivery of miRNAs for cancer therapy: challenges and strategies

Y Chen, DY Gao, L Huang - Advanced drug delivery reviews, 2015 - Elsevier
… The strategies employed in in vivo miRNA delivery for cancer therapy are … miRNA delivery
and enhance the efficacy of cancer therapy. The first strategy developed for systemic delivery

A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
… of therapeutic miRNA delivery systems that includes virus-based delivery, non-viral delivery
(… expression versatility emphasizes their utility in cancer therapeutic strategies. Therefore, …

MicroRNA delivery by cationic lipoplexes for lung cancer therapy

Y Wu, M Crawford, B Yu, Y Mao… - Molecular …, 2011 - ACS Publications
… is faced with several challenges including lack of tissue specificity, lack of optimal delivery
miRNA delivery system to address some of these challenges. Among many lung cancer

Overcoming obstacles in microRNA delivery towards improved cancer therapy

D Ben-Shushan, E Markovsky, H Gibori… - Drug delivery and …, 2014 - Springer
… is an urgent need for efficient methods to deliver miRNAs. These can be divided into three
… considerations for miRNA delivery for cancer therapy, focusing on nonviral delivery systems…

Therapeutic microRNA delivery strategies with special emphasis on cancer therapy and tumorigenesis: current trends and future challenges

C Chakraborty, ZH Wen… - Current drug …, 2016 - ingentaconnect.com
therapeutic microRNA delivery strategies and also briefly discuss the different miRNA delivery
… based (LNA-based) compounds delivery without any delivery-mediated agent. Finally, we …

Tumor‐targeted Delivery of Anti‐microRNA for Cancer Therapy: pHLIP is Key

E Wagner - Angewandte Chemie International Edition, 2015 - Wiley Online Library
… pHLIP opens the door to the cell: An improved cytosolic transfer of anti-microRNAs (anti-miRs)
against onco-miRs paves the way for future cancer therapies. The employed anti-miR–…

MicroRNA replacement therapy in cancer

H Mollaei, R Safaralizadeh… - Journal of cellular …, 2019 - Wiley Online Library
… on the delivery of therapeutic miRNAs into cancerous cells and … evidence addressing
miRNA-based therapeutic approaches … delivery approach to offer effective miRNA cancer therapy. …

Tumor associated macrophage-targeted microRNA delivery with dual-responsive polypeptide nanovectors for anti-cancer therapy

L Liu, H Yi, H He, H Pan, L Cai, Y Ma - Biomaterials, 2017 - Elsevier
… developed for TAM-targeted miR delivery and anti-cancer therapy. The core of nanovectors
… -targeted miR delivery. The results showed that sPEG/GLC successfully delivered miR155 …

Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34

JF Wiggins, L Ruffino, K Kelnar, M Omotola… - Cancer research, 2010 - AACR
… systemic delivery of a synthetic tumor suppressor mimic, obviating obstacles associated
with viral-based miRNA delivery and facilitating a rapid route for miRNA replacement therapy