… pro-cancer and pro-death roles of mitophagy. Finally, we summarise the role of … in
cancer therapy. Mitophagy can potentially be acted as the target for cancer therapy by …

… However, with dose escalations, autophagy did not change to apoptosis in response to these
anticancer therapies, suggesting that the role played by mitochondria in autophagy may be …

… was inhibited at the lysosome fusion stage (with bafilomycin A1 or RTA203), cell death
increased with an associated loss in mitochondrial membrane potential. This study suggests that …

… The increased potential of the mitochondrial network to produce ATP, together with … of
autophagy which is of specific importance to cancer metabolism (discussed later in this review). …

… through the ULK1 complex, (3) disruption of BECLIN1–BCL-2 interaction leading to the
initiation of autophagy or (4) alteration of mitochondria homeostasis leading to mitophagy …

… signaling pathways as targets for future cancer therapy. Autophagy is an evolutionarily highly
… cells toward camptothecin induced mitochondrial damage and cell death.The present list of …

… While autophagy inhibition by RNA interference or … indeed autophagy-based alteration of
mitochondrial metabolism … of autophagic recycling hampered the capacity of mitochondria to …

… autophagy in cancer cells, making autophagy an attractive process to focus on in cancer
therapy… identified as the selective receptor for mitochondria autophagic clearance, or mitophagy.…

… Genetic or pharmacologic inhibition of autophagy also reduces mitochondrial oxidative
phosphorylation in pancreatic ductal adenocarcinoma cells. These findings indicate that …

… Macroautophagy involves the formation of double membrane vesicles that engulf
proteins and organelles, such as mitochondria and peroxisomes. These vesicles, called …