… mitochondria.68 We hypothesized that melatonin may induce apoptosis as well as autophagy
… Lysosomal degradation of autophagosomes leads to a drop in p62 levels. After treatment …

… active compounds lead to ultra-structural perturbations; changes in membrane composition,
cytoskeleton integrity, alterations of the endoplasmic reticulum, mitochondria and nucleus all …

… , is involved in mitophagy (mitochondrial autophagy). Both p62 and BNIP3 … autophagy
inhibitors are already being tested in clinical trials and hold promise for combined cancer therapies…

… autophagy helps maintain a pool of healthy mitochondria by causing the degradation of
defective mitochondria (… These questions suggest that modulating autophagy for cancer therapy …

… autophagy results in cell death or survival.14 It is becoming progressively clear how crucial
autophagic cell death is for cancer therapy … as well as on the mitochondria.16, 18 This EGFR …

… tumors; therefore autophagy inhibition suppresses tumor … the role of autophagy in
tumorigenesis and cancer therapy. … and growth; autophagy inhibits apoptosis caused by …

… -targeting of mitochondria as part of anticancer therapy. Here, … mitochondria in cancer and
non-cancer cells and demonlow … may induce autophagy in both cancer and non-cancer cells. …

… an increased dependence on autophagy and mitochondrial function, including β-… cancer
therapies has been shown to induce autophagy and in most cases, although not all, autophagy …

… in defining mitophagy regulation in mitochondria and the role of mitophagy … cancer therapy
remains an unsolved topic. Therefore, in this review, the role of autophagy and mitochondrial …

… , by eliminating damaged mitochondria for … in cancer therapy is to achieve as much tumor
cell killing as possible, the strategy for exploiting the nanomaterial-elicited autophagy in cancer …