T regulatory cells in cancer: recent advances and therapeutic potential

E Elkord, EM Alcantar-Orozco, SJ Dovedi… - … on biological therapy, 2010 - Taylor & Francis
Importance of the field: The active suppression of immune responses against tumor is a major
barrier to the likely success of cancer immunotherapy. There is now compelling evidence …

Long noncoding RNAs in cancer and therapeutic potential

A Renganathan, E Felley-Bosco - Long Non Coding RNA Biology, 2017 - Springer
… In addition, special focus has been given on the efficient application of lncRNAs as
potential targets for therapeutics that holds a great promise for future cancer therapy. …

Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives

JK Kundu, YJ Surh - Cancer letters, 2008 - Elsevier
… 1 illustrates the biochemical basis of cancer chemopreventive and therapeutic potential of
resveratrol. The chemopreventive property of resveratrol has been reflected by its ability to …

[HTML][HTML] Endoplasmic reticulum stress response in cancer: molecular mechanism and therapeutic potential

G Wang, ZQ Yang, K Zhang - American journal of translational …, 2010 - ncbi.nlm.nih.gov
… has inspired great interest in exploring therapeutic potentials by targeting the UPR … in
cancer therapy. In the following, we provide some representative evidence for cancer therapeutic

The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential

SP Becerra, V Notario - Nature Reviews Cancer, 2013 - nature.com
… applications to cancer therapy. This has led to the identification of PEDF as a major antagonist
to angiogenic factors (such as vascular endothelial growth factor (VEGF)), evidence for its …

Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer

A Schultze, W Fiedler - Expert opinion on investigational drugs, 2010 - Taylor & Francis
… What the reader will gain: This review enables the reader to overview current knowledge
about FAK inhibition in cancer therapy and its role in the clinical setting. The reader will be able …

Combination therapy with histone deacetylase inhibitors (HDACi) for the treatment of cancer: achieving the full therapeutic potential of HDACi

A Suraweera, KJ O'Byrne, DJ Richard - Frontiers in oncology, 2018 - frontiersin.org
… We additionally highlight the side effects associated with HDACi in cancer therapy and
discuss potential biomarkers to either select or predict a patient’s response to these agents, in …

Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential

AS Lee - Nature Reviews Cancer, 2014 - nature.com
… , as well as their biological functions in cancer. Promising agents that use or target the
GRPs are being developed, and their efficacy as anticancer therapeutics is also discussed. …

Novel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancer

FEB May - Cancer management and research, 2014 - Taylor & Francis
The incidence of breast cancer continues to rise: 1.7 million women were diagnosed with
and 521,000 women died from breast cancer in 2012. This review considers first current …

Therapeutic potential of interleukin-15 in cancer

G Isvoranu, M Surcel… - … and therapeutic …, 2021 - spandidos-publications.com
… These three therapeutic approaches are named by the experts as ‘the pillars of cancer therapy’…
The concept of single therapy in cancer therapy has been discounted with each discovery …