Macrophages as tools and targets in cancer therapy

A Mantovani, P Allavena, F Marchesi… - Nature Reviews Drug …, 2022 - nature.com
… Here, we will review strategies to exploit macrophages as therapeutic tools and targets in
cancer therapy, including the role of TAMs in conventional anticancer therapies and …

MicroRNAs as novel targets and tools in cancer therapy

ML Abba, N Patil, JH Leupold, M Moniuszko, J Utikal… - Cancer letters, 2017 - Elsevier
therapeutic potential of miRNAs. Therefore, this review focuses on the recent development of
(1) how miRs have become therapeutic targets … might emerge as tools to counter the activity …

Targeted cancer therapy: the next generation of cancer treatment

TA Baudino - Current drug discovery technologies, 2015 - ingentaconnect.com
… In an attempt to target only cancer cells, a new generation of cancer treatment has arisen, …
are becoming useful tools for oncologists in the treatment of cancer patients. Patients are able …

MicroRNAs as new therapeutic targets and tools in cancer

P Gandellini, V Profumo, M Folini… - … on therapeutic targets, 2011 - Taylor & Francis
… the pathogenesis of cancer. As they can act as either oncogenes or tumor suppressors,
miRNAs have been proposed as potential new therapeutic targets or tools for cancer therapy. …

Novel points of attack for targeted cancer therapy

GV Røsland, AST Engelsen - Basic & clinical pharmacology & …, 2015 - Wiley Online Library
… provide the tools required to enable oncologists to tailor cancer treatment to the individual …
cells, EGFR has long been an attractive molecular target for cancer therapy. Attempts to target

Neuropilins: a new target for cancer therapy

C Grandclement, C Borg - Cancers, 2011 - mdpi.com
… and identified as an attractive angiogenesis target for cancer therapy, the NRP2 signaling
… multiples functions in cancer promotion, NRPs fulfill all the criteria of a therapeutic target for …

Identification of novel targets for cancer therapy using expression proteomics

SM Hanash, J Madoz-Gurpide, DE Misek - Leukemia, 2002 - nature.com
… for drug target discovery. Although the field is still in the early stages, current proteomic
tools … , leading to discovery of novel drug targets. Proteomics uniquely allows delineation of …

Novel and emerging targeted-based cancer therapy agents and methods

M Hojjat-Farsangi - Tumor Biology, 2015 - Springer
… agents has sparked further therapeutic modalities with novel targets to inhibit. Due to the lack
… and anti-CD274 mAbs are described briefly as interesting tools for targeted cancer therapy. …

[HTML][HTML] Targeting Mnks for cancer therapy

J Hou, F Lam, C Proud, S Wang - Oncotarget, 2012 - ncbi.nlm.nih.gov
… that a targeted therapeutic agent inhibiting a single target or … redundant network, allowing
some cancer cells to survive or … chemical biology tools for pharmacological target validation …

The tumour microenvironment: a novel target for cancer therapy

E Hanna, J Quick, SK Libutti - Oral diseases, 2009 - Wiley Online Library
therapy will likely involve the combination of one or more agents directed at this new
target. … involving agents that target tumour vasculature, leucocytes, pericytes, cancer-associated …