Therapeutic prospects of extracellular vesicles in cancer treatment

DS Chulpanova, KV Kitaeva, V James… - Frontiers in …, 2018 - frontiersin.org
… In addition, the lower extracellular pH can promote tumor resistance to cytotoxic drugs …
acidic vesicles and/or eliminating them through an exocytotic pathway (29). Extracellular vesicles

Biomedical application of small extracellular vesicles in cancer treatment

S Araujo-Abad, M Saceda… - Advanced drug delivery …, 2022 - Elsevier
… , biomolecules, cancer drugs, etc., and can be developed for a specific cancer treatment. …
treatment of several cancer types aiming to improve the prognosis of these deadly diseases. …

[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment

S Walker, S Busatto, A Pham, M Tian, A Suh… - Theranostics, 2019 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …

Harnessing the therapeutic potential of extracellular vesicles for cancer treatment

Y Zhang, Y Xiao, G Sun, X Jin, L Guo, T Li… - Seminars in Cancer …, 2021 - Elsevier
… However, current cancer treatment still faces challenges such as … specificity, due to the
complexity of the cancer environment. … of EV use in cancer treatment from bench to bedside, to …

Mechanisms of drug resistance in cancer: the role of extracellular vesicles

P Samuel, M Fabbri, DRF Carter - Proteomics, 2017 - Wiley Online Library
… for managing cancer treatment. While further characterization of the vesiculome and the
mechanisms of EV function are still required, EVs offer an exciting opportunity in the fight against …

Extracellular vesicles-based drug delivery system for cancer treatment

B Balachandran, Y Yuana - Cogent Medicine, 2019 - Taylor & Francis
… As cancers can continuously adapt towards treatments, development of DDS to target specific
cancer and to treat different type or stage of cancers is needed. The extracellular vesicles (…

Extracellular vesicles: toward a clinical application in urological cancer treatment

F Urabe, N Kosaka, T Kimura… - … Journal of Urology, 2018 - Wiley Online Library
cancers. Here, we summarize the current research … extracellular vesicles in urological
cancer and discuss potential clinical applications for extracellular vesicles in urological cancer. …

The small vesicular culprits: the investigation of extracellular vesicles as new targets for cancer treatment

F Urabe, N Kosaka, Y Yoshioka, S Egawa… - Clinical and translational …, 2017 - Springer
… Despite being classified by the origin of these vesicles, we … vesicles in the extracellular
milieu, according to the recommendation of the International Society for Extracellular Vesicles

Adult stem cell-derived extracellular vesicles in cancer treatment: opportunities and challenges

V Parfejevs, K Sagini, A Buss, K Sobolevska… - Cells, 2020 - mdpi.com
Cancer treatment is one of the most promising applications of SC-EVs. Moreover, SC-EVs …
cancer treatment and to emphasise future opportunities and challenges in cancer treatment. …

[HTML][HTML] Extracellular vesicles as an emerging drug delivery system for cancer treatment: Current strategies and recent advances

Z Wang, H Mo, Z He, A Chen, P Cheng - Biomedicine & Pharmacotherapy, 2022 - Elsevier
… (EVs) are natural nano-sized lipid bilayer vesicles secreted … cancer treatment. In this review,
we summarize the research progress of EV-based drug delivery systems in cancer treatment