Cancer chemotherapy and heterocyclic compounds

M Kidwai, R Venktaramanan… - Current medicinal …, 2002 - ingentaconnect.com
Cancer chemotherapy is now of established value and a highly specialized field. Among
the modifications to the family of antitumor compounds, heterocyclic … of heterocycles which …

[PDF][PDF] The importance of heterocyclic compounds in anti-cancer drug design

S Pearce - Drug Discovery, 2017 - ddw-online.com
… Indeed, of the novel molecular anti-cancer agents approved … heterocyclic compounds currently
implicated in cancer therapy, … as anti-cancer drugs, and consider the benefits of including …

Anti-cancer nitrogen-containing heterocyclic compounds

Z Hosseinzadeh, A Ramazani… - Current Organic …, 2018 - ingentaconnect.com
heterocycles as possible chemotherapy agents for cancer. A simple gleam at FDA databases
shows the structural importance of nitrogen-based heterocycles in … protein molecules with …

Heterocyclic scaffolds: centrality in anticancer drug development

I Ali, M Nadeem Lone, ZA Al-Othman… - Current drug …, 2015 - ingentaconnect.com
cancer treatment. The researchers all the world over are trying to incorporate different heterocyclic
moieties into various molecules … We hope that some potent heterocyclic molecules will …

[HTML][HTML] Heterocyclic anticancer compounds: recent advances and the paradigm shift towards the use of nanomedicine's tool box

P Martins, J Jesus, S Santos, LR Raposo… - Molecules, 2015 - mdpi.com
… compound for cancer treatment through a well-designed in vitro and in vivo experimentation
[30]. SK228 was capable of inhibiting cell growth of human lung and esophageal …

[HTML][HTML] Heterocyclic Molecular Targeted Drugs and Nanomedicines for Cancer: Recent Advances and Challenges

J Liu, T Chao, Y Liu, C Gong, Y Zhang, H Xiong - Pharmaceutics, 2023 - mdpi.com
… have taken targeted cancer therapy to a new level. In this review, we highlight heterocyclic
molecular-targeted drugs as well as heterocyclic-associated nanomedicines in cancer. …

Advancement in the development of heterocyclic nucleosides for the treatment of cancer-A review

AZ Mirza - Nucleosides, Nucleotides and Nucleic Acids, 2019 - Taylor & Francis
treatment of cancer diseases. Nucleoside, nucleotide and base analogues have been utilised
for decades for the treatment of … Also, it depicts the development of heterocyclic nucleoside …

[PDF][PDF] FDA-approved heterocyclic molecules for cancer treatment: Synthesis, dosage, mechanism of action and their adverse effect

M Hossain, I Habib, K Singha, A Kumar - Heliyon, 2024 - cell.com
… -cancer activity. Here in this review, we classified some molecules and biologically active
heterocycles … on their use in various forms of cancer. We will focus on those that are suitable for …

Oxygen-and sulphur-containing heterocyclic compounds as potential anticancer agents

H Sachdeva, S Khaturia, M Saquib, N Khatik… - Applied Biochemistry …, 2022 - Springer
cancer is difficult. Hence, researchers are trying to synthesize new fused/spiro heterocyclic
molecules … Furthermore, fused heterocycles behave as DNA intercalating agents which have …

Heterocyclic Compounds: Importance in Anticancer Drug Discovery

N Kumar, N Goel - … Current Medicinal Chemistry-Anti-Cancer …, 2022 - ingentaconnect.com
heterocyclicbased lead molecules [15]. In this review, we have discussed the vital heterocyclic
moieties which are utilized in cancer treatment… that make them potential anticancer drugs. …