Cancer therapeutics: understanding the mechanism of action

RC Cattley, BR Radinsky - Toxicologic pathology, 2004 - journals.sagepub.com
… new strategic targets for the treatment of cancer. The sizeable efforts … cancer cell phenotype
indicate the potential utility of investigation into the mechanism of action of these anti-cancer

Bisphosphonates for cancer treatment: mechanisms of action and lessons from clinical trials

HH Van Acker, S Anguille, Y Willemen, EL Smits… - Pharmacology & …, 2016 - Elsevier
… The use of bisphosphonates in cancer therapy definitely warrants further investigation to
establish their role as a potential (adjuvant) cancer treatment. Current research efforts strive to …

[HTML][HTML] Electroporation as a new cancer treatment technique: a review on the mechanisms of action

A Yadollahpour, Z Rezaee - … and Pharmacology Journal, 2015 - biomedpharmajournal.org
cancer treatment, different studies should be performed to determine the mechanisms of action
… studies can shed light on the different aspects of mechanisms of action of this technique. …

Aromatase inhibitors: mechanism of action and role in the treatment of breast cancer

WR Miller - Seminars in oncology, 2003 - Elsevier
The natural history of breast cancer is closely linked with … synthesis or block the mechanism
of action of estrogens are … with hormone-dependent breast cancer. They also represent tools …

Histone deacetylase inhibitors: mechanism of action and therapeutic use in cancer

O Martínez-Iglesias, L Ruiz-Llorente… - Clinical and …, 2008 - Springer
… ) constitute a promising treatment for cancer therapy due to … invasion, and angiogenesis in
many cancer cell lines. In addition, … be advantageous in cancer treatment over paninhibition of …

The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action

GYL Lui, P Obeidy, SJ Ford, C Tselepis, DM Sharp… - Molecular …, 2013 - ASPET
… may have potential applications in cancer treatment. However, no … Additionally, its mechanism
of action remains poorly … , and dissect its molecular mechanism of action by examining its …

Cisplatin in cancer therapy: molecular mechanisms of action

S Dasari, PB Tchounwou - European journal of pharmacology, 2014 - Elsevier
… Cisplatin derivatives are used as the mainline treatment of ovarian cancer, despite their …
other chemical agents or compounds to treat ovarian cancer in both the resistant and sensitive …

Interferon-α and cancer: mechanisms of action and new perspectives of clinical use

M Ferrantini, I Capone, F Belardelli - Biochimie, 2007 - Elsevier
… been performed in cancer patients, especially in patients with melanoma [12], showing
variable results. While all this did not result in a major advance in cancer treatment, the ensemble …

Mechanisms of action of therapeutic antibodies for cancer

JM Redman, EM Hill, D AlDeghaither, LM Weiner - Molecular immunology, 2015 - Elsevier
… of human diseases, including many types of cancer. The class of antibody most frequently
… are mainstays of some breast and colon cancer treatment algorithms. By directly binding to …

PARP inhibitors: mechanism of action and their potential role in the prevention and treatment of cancer

B Basu, SK Sandhu, JS De Bono - Drugs, 2012 - Springer
… Potentially, an intermittent course of treatment repeated over years may result in long-term
cancer prophylaxis and, in view of the relatively manageable side-effect profile of most …