… cancer metabolism and how it may be harnessed to enhance ongoing experimental efforts to
identify drug targets and biomarkers for cancer … previously published and validated (Table 2…

… cervical cancer patients. Immunotherapy has become a new treatment modality for cervical
cancer patients, and there is an urgent need to identify additional targets for cervical cancer …

… targets have been validated both in vitro and in vivo. The technologies developed to do this
have not only yielded a significant number of drug targets but … attractive targets in cancer. In …

… means an extensive list, and points to a busy future for lung cancer researchers – just under
50% of lung cancers need therapeutic approaches to be matched to their validated targets. …

… -positive cancers, and the implications for novel treatment. … While the clinical potential of
novel therapeutic targets … clinical validation of the signature and preclinical validation of the …

… validated or confirmed to correlate with the definitive cancer end point. For example, the
short-term clinical response rate of a potential SEB in oral IEN was only marginally associated …

… Finally, we used a large-scale drug screen to validate our approach for inferring
druggability across human cancers. By applying and validating novel approaches for inferring …

… of miRNAs in cancer pathogenesis, miRNAs not only become promising targets for cancer
therapy but show … The discovery history of several validated SMIRs is reviewed at the end. …

… After EGFR and other tyrosine kinases had been validated as suitable pharmacological
targets for anticancer drugs, one of the hottest races in pharmaceutical development began — to …

… proteomics analysis and functional validation studies using … targets for eradicating cancer
stem cells, to prevent tumor recurrence, metastasis and poor clinical outcome in breast cancer …