Caspofungin Affects Extracellular Vesicle Production and Cargo in Candida auris

RF Amatuzzi, D Zamith-Miranda, IF Munhoz da Rocha… - Journal of Fungi, 2022 - mdpi.com
… Among these fungal species of global threat, Candida auris stands out for commonly …
infections varies from 28% to 78%. In this study, we characterized C. auris extracellular vesicles (…

Extracellular vesicles of Candida albicans regulate its own growth through the l-arginine/nitric oxide pathway

Y Wei, Z Wang, Y Liu, B Liao, Y Zong, Y Shi… - Applied Microbiology …, 2023 - Springer
Candida albicans is the main conditional pathogenic fungus among the human microbiome.
Extracellular vesicles (EVs) … Candida albicans is one of the most common opportunistic …

A comparative analysis of protein virulence factors released via extracellular vesicles in two Candida albicans strains cultivated in a nutrient-limited medium

K Konečná, J Klimentová, O Benada, I Němečková… - Microbial …, 2019 - Elsevier
extracellular vesicles (EVs). Only a few studies aimed at investigating Candida albicans
extracellular vesiclesalbicans infections have been conducted to date. In this study, we mainly …

Extracellular Vesicles from Candida haemulonii var. vulnera Modulate Macrophage Oxidative Burst

BTM Oliveira, TMH Dourado, PWS Santos… - Journal of Fungi, 2023 - mdpi.com
… superficial and invasive infections in risk populations. Fungal extracellular vesicles (EVs) …
and may perform essential functions during infections, such as carrying virulence factors that …

Extracellular vesicles of human pathogenic fungi

E Bielska, RC May - Current opinion in microbiology, 2019 - Elsevier
fungal pathophysiology and host–pathogen interactions. Recent findings have revealed a role
for fungal vesicles in … current understanding of fungal extracellular vesicles, including their …

Small extracellular vesicles secreted by Candida albicans hyphae have highly diverse protein cargoes that include virulence factors and stimulate macrophages

R Martínez-López, ML Hernáez, E Redondo, G Calvo… - bioRxiv, 2020 - biorxiv.org
Extracellular vesicles (EVs) have been described as … In Candida albicans, a relevant
commensal fungal pathogen, the dimorphic transition is an important virulence trait in candidiasis. …

Coordination of fungal biofilm development by extracellular vesicle cargo

R Zarnowski, A Noll, MG Chevrette, H Sanchez… - Nature …, 2021 - nature.com
fungal pathogen Candida albicans can form biofilms that protect it from drugs and the
immune system. The biofilm cells release extracellular vesicles (EVs) that promote extracellular

Induction of amphotericin B resistance in susceptible Candida auris by extracellular vesicles

W Chan, FWN Chow, CC Tsang, X Liu… - … Microbes & Infections, 2022 - Taylor & Francis
Drug resistance derived from extracellular vesicles (EVs) is an increasingly important
research area but has seldom been described regarding fungal pathogens. Here, we …

Extracellular vesicles contribute to mixed-fungal species competition during biofilm initiation

R Zarnowski, J Massey, AP Mitchell, D Andes - MBio, 2022 - Am Soc Microbiol
Candida biofilms. (A) Biofilm adhesion over 90 min of incubation of the Candida extracellular
vesicle cargo … Concentrations of Candida biofilm extracellular vesicles during early biofilm …

Mass Spectrometry Analysis Reveals Lipids Induced by Oxidative Stress in Candida albicans Extracellular Vesicles

G Trentin, TA Bitencourt, A Guedes, AM Pessoni… - Microorganisms, 2023 - mdpi.com
… response alters the fungal cells’ metabolism [9] and may also affect the EVs’ release and
content [32]. The impact of oxidative stress over Candida albicans extracellular vesicles is still …