IBD candidate genes and intestinal barrier regulation

DF McCole - Inflammatory bowel diseases, 2014 - academic.oup.com
… This article will discuss IBD candidate genes that are known to be, or are suspected of
being, involved in regulating the intestinal epithelial barrier and several of the physiological …

Systems genetics: a paradigm to improve discovery of candidate genes and mechanisms underlying complex traits

FA Feltus - Plant Science, 2014 - Elsevier
… or selects proximal candidate genes via prior … gene may not be known, the candidate gene
approach is often unsuccessful or tempts the researcher to continue to try to fit the gene into a …

Identification and functional analysis of candidate genes regulating mesenchymal stem cell self‐renewal and multipotency

L Song, NE Webb, Y Song, RS Tuan - Stem cells, 2006 - academic.oup.com
… Taken together, these results confirmed our hypothesis and proved the effectiveness of
our system to identify candidate genes controlling stem cell self‐renewal and multipotency. …

Candidate genes and their regulatory elements: alcohol preference and tolerance

L Saba, SV Bhave, N Grahame, P Bice, R Lapadat… - Mammalian …, 2006 - Springer
… With regard to the “trans”-regulated candidate genes that we … candidate genes for transcription
factor genes and pay attention to whether the regulatory regions of the candidate genes

Convergent functional genomics of genome‐wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

H Le‐Niculescu, SD Patel, M Bhat… - … of Medical Genetics …, 2009 - Wiley Online Library
… and canonical pathways of the top candidate genes resulting from our CFG analysis (Fig.
3), as well as to identify genes in our datasets that are the target of existing drugs (Table IIS). …

Candidate gene association studies: a comprehensive guide to useful in silicotools

R Patnala, J Clements, J Batra - BMC genetics, 2013 - Springer
… with prior knowledge about gene function. The candidate gene approach begins with selection
of a putative candidate gene based on its relevance in the mechanism of the disease (trait…

Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approach

ZA Rodd, BA Bertsch, WN Strother… - The …, 2007 - nature.com
… approach for identifying candidate genes for alcoholism. The approach relies on the cross-matching
of animal model brain gene expression data with human genetic linkage data, as …

Candidate genes and mechanisms for 2-methoxyestradiol–mediated vasoprotection

F Barchiesi, E Lucchinetti, M Zaugg, OO Ogunshola… - …, 2010 - Am Heart Assoc
… Identification of candidate genes that are positively or negatively regulated by 2-ME
provides important leads to investigate and better understand the mechanisms by which 2-ME …

[HTML][HTML] Genomic architecture of promoters and transcriptional regulation of candidate genes in rice involved in tolerance to anaerobic germination

B Mohanty - Current Plant Biology, 2022 - Elsevier
… by unique transcriptional regulatory mechanisms that … regulation is essentially unknown.
Hence, a comprehensive understanding of the gene regulation of these candidate genes can …

In silico analyses for molecular genetic mechanism and candidate genes in patients with Alzheimer's disease

LM Chi, X Wang, GX Nan - Acta Neurologica Belgica, 2016 - Springer
… This study aimed to identify candidate genes and explore the molecular pathogenesis of
Alzheimer’s disease (AD). Exon microarray data composed by of three human entorhinal cortex …