Molecular cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal domain suggests functional divergence among capsaicin receptor …

MA Schumacher, I Moff, SP Sudanagunta… - Journal of Biological …, 2000 - ASBMB
… other subtypes of the capsaicin receptor. A cDNA was isolated that diverges with VR1 at its
5′ end and is termed VR.5′sv. It is predicted to encode a capsaicin receptor subunit with a …

Beyond neuronal heat sensing: diversity of TRPV1 heat-capsaicin receptor-channel functions

YM Shuba - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
… Disruption of the Trpv1 gene in mice deprived animals of principal in vivo responses thought
to be linked to putative capsaicin receptor function: eliminated capsaicin and RTX sensitivity …

Pharmacology of the capsaicin receptor, transient receptor potential vanilloid type-1 ion channel

I Nagy, D Friston, JS Valente, JVT Perez… - Capsaicin as a …, 2014 - Springer
… ), the capsaicin receptor, then called as vanilloid type 1 receptor, was … of capsaicin and its
receptor the transient receptor potential … of the pharmacology of the capsaicin receptor, TRPV1. …

Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels

CB Phelps, E Procko, PV Lishko, RR Wang, R Gaudet - Channels, 2007 - Taylor & Francis
… to capsaicin in … capsaicin applications, normalized to the current amplitudes obtained on
the first application (B) and mean current density of the maximal response to the first capsaicin

Capsaicin, nociception and pain

B Frias, A Merighi - Molecules, 2016 - mdpi.com
… The capsaicin receptor, named transient receptor potential vanilloid 1 … in pharmacological
responses between TRPV1 and native capsaicin receptors for the presence of regulatory …

Vanilloid (capsaicin) receptors in health and disease

A Szallasi - American journal of clinical pathology, 2002 - academic.oup.com
… Molecular cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal
domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem. …

Capsaicin-sensitive afferents and their role in gastroprotection: an update

J Szolcsanyi, L Bartho - Journal of Physiology-Paris, 2001 - Elsevier
… In addition, several signs of mismatches between sensation and local efferent vascular
responses embodied already in our concept (see later) for the dual function of capsaicin-…

Functional diversity and evolutionary dynamics of thermoTRP channels

S Saito, M Tominaga - Cell Calcium, 2015 - Elsevier
… On the other hand, characterization of rabbit TRPV1 identified another amino acid residue
involved in sensitivity to capsaicin. Sensitivity of rabbit TRPV1 to capsaicin is also low and …

TRPV1 (vanilloid receptor, capsaicin receptor) agonists and antagonists

G Appendino, E Muñoz, BL Fiebich - Expert Opinion on …, 2003 - Taylor & Francis
… the results of assays carried out on native receptors in DRG cells and on cloned receptors
in transfected cells. Finally, divergences have also been observed between affinity data based …

Similarities and differences in the structure− activity relationships of capsaicin and resiniferatoxin analogues

CSJ Walpole, S Bevan, G Bloomfield… - Journal of medicinal …, 1996 - ACS Publications
… in simple capsaicin analogues has little or no role in RTX analogues. This divergence in SAR
is particularly apparent when comparing the coupled pairs 3b with 5b (capsaicin analogues…