Molecular cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal domain suggests functional divergence among capsaicin receptor …
MA Schumacher, I Moff, SP Sudanagunta… - Journal of Biological …, 2000 - ASBMB
… other subtypes of the capsaicin receptor. A cDNA was isolated that diverges with VR1 at its
5′ end and is termed VR.5′sv. It is predicted to encode a capsaicin receptor subunit with a …
5′ end and is termed VR.5′sv. It is predicted to encode a capsaicin receptor subunit with a …
Beyond neuronal heat sensing: diversity of TRPV1 heat-capsaicin receptor-channel functions
YM Shuba - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
… Disruption of the Trpv1 gene in mice deprived animals of principal in vivo responses thought
to be linked to putative capsaicin receptor function: eliminated capsaicin and RTX sensitivity …
to be linked to putative capsaicin receptor function: eliminated capsaicin and RTX sensitivity …
Pharmacology of the capsaicin receptor, transient receptor potential vanilloid type-1 ion channel
… ), the capsaicin receptor, then called as vanilloid type 1 receptor, was … of capsaicin and its
receptor the transient receptor potential … of the pharmacology of the capsaicin receptor, TRPV1. …
receptor the transient receptor potential … of the pharmacology of the capsaicin receptor, TRPV1. …
Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels
… to capsaicin in … capsaicin applications, normalized to the current amplitudes obtained on
the first application (B) and mean current density of the maximal response to the first capsaicin …
the first application (B) and mean current density of the maximal response to the first capsaicin …
Capsaicin, nociception and pain
B Frias, A Merighi - Molecules, 2016 - mdpi.com
… The capsaicin receptor, named transient receptor potential vanilloid 1 … in pharmacological
responses between TRPV1 and native capsaicin receptors for the presence of regulatory …
responses between TRPV1 and native capsaicin receptors for the presence of regulatory …
Vanilloid (capsaicin) receptors in health and disease
A Szallasi - American journal of clinical pathology, 2002 - academic.oup.com
… Molecular cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal
domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem. …
domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem. …
Capsaicin-sensitive afferents and their role in gastroprotection: an update
J Szolcsanyi, L Bartho - Journal of Physiology-Paris, 2001 - Elsevier
… In addition, several signs of mismatches between sensation and local efferent vascular
responses embodied already in our concept (see later) for the dual function of capsaicin-…
responses embodied already in our concept (see later) for the dual function of capsaicin-…
Functional diversity and evolutionary dynamics of thermoTRP channels
S Saito, M Tominaga - Cell Calcium, 2015 - Elsevier
… On the other hand, characterization of rabbit TRPV1 identified another amino acid residue
involved in sensitivity to capsaicin. Sensitivity of rabbit TRPV1 to capsaicin is also low and …
involved in sensitivity to capsaicin. Sensitivity of rabbit TRPV1 to capsaicin is also low and …
TRPV1 (vanilloid receptor, capsaicin receptor) agonists and antagonists
G Appendino, E Muñoz, BL Fiebich - Expert Opinion on …, 2003 - Taylor & Francis
… the results of assays carried out on native receptors in DRG cells and on cloned receptors
in transfected cells. Finally, divergences have also been observed between affinity data based …
in transfected cells. Finally, divergences have also been observed between affinity data based …
Similarities and differences in the structure− activity relationships of capsaicin and resiniferatoxin analogues
CSJ Walpole, S Bevan, G Bloomfield… - Journal of medicinal …, 1996 - ACS Publications
… in simple capsaicin analogues has little or no role in RTX analogues. This divergence in SAR
is particularly apparent when comparing the coupled pairs 3b with 5b (capsaicin analogues…
is particularly apparent when comparing the coupled pairs 3b with 5b (capsaicin analogues…
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