… carbapenem-hydrolyzing oxacillinases contribute significantly to resistance to carbapenems
… nosocomial outbreak by a multiresistant Acinetobacter baumannii strain with a carbapenem-…

… Alignment of amino-acid sequences of the four main groups of carbapenem-hydrolysing
class D β-lactamases (CHDLs) identified in Acinetobacter baumannii, including OXA-23, OXA-…

… Acinetobacter baumannii, a Gram negative bacterium causes nosocomial infections including
… baumannii has been global concern. Till recently, carbapenems, latest generation of β-…

… presence of an imipenem-hydrolyzing enzyme. The observed carbapenem resistance correlated
… was observed during the measurement of imipenem hydrolysis in the presence of 1 mM …

… baumannii including the novel MBL blaNDM-1. The present study was carried out to identify
… of multiple carbapenem hydrolyzing enzymes among the clinical isolates of A. baumannii. …

… rounding the active site of OXA-40 with those of other class D βlactamases did not provide
an explanation for the ability of OXA40 to hydrolyse carbapenems while demonstrating a …

A carbapenem-resistant Acinetobacter baumannii strain was isolated in Brazil in 2004 in
which no known carbapenemase gene was detected by PCR. Cloning experiments, followed …

… at DBL position 144 in conferring carbapenem-hydrolyzing activity, we performed a Tyr-to-…
, an oxacillinase that does not possess significant carbapenem-hydrolyzing activity (19). A site-…

… site, hydrolyzes additionally carbapenems, but at a … carbapenem and cephamycin hydrolysis.
GES-9, which differs from GES-1 by a Gly243Ser change, does not hydrolyze carbapenems …

… ), are the most commonly reported carbapenem resistance determinants in Acinetobacter
spp., particularly in Acinetobacter baumannii. In the genus Acinetobacter, various intrinsic OXA …