[HTML][HTML] Global spread of carbapenemase-producing Enterobacteriaceae

P Nordmann, T Naas, L Poirel - Emerging infectious diseases, 2011 - ncbi.nlm.nih.gov
… of β-lactamases: the Ambler class A, B, and D β-lactamases (2). In … gene are diverse and
can harbor a high number of resistance genes associated with other carbapenemase genes

[HTML][HTML] … role of the natural aquatic environment in the dissemination of extended spectrum beta-lactamase and carbapenemase encoding genes: A scoping review

B Hooban, A Joyce, K Fitzhenry, C Chique, D Morris - Water Research, 2020 - Elsevier
… , namely, extended spectrum beta-lactamase (ESBL) and carbapenemase genes. This review
… ESBL genes were reported in 29/41 (70.7%) studies, while carbapenemase genes were …

[HTML][HTML] Carbapenemase genes and genetic platforms in Gram-negative bacilli: Enterobacteriaceae, Pseudomonas and Acinetobacter species

SM Diene, JM Rolain - Clinical Microbiology and Infection, 2014 - Elsevier
… -lactamase inhibitors, including clavulanic acid and tazobactam; and (ii) metallo-β-lactamases
belonging to the class B carbapenemases, … the bicyclic β-lactam ring. These enzymes are …

Metagenomic analysis of β-lactamase and carbapenemase genes in the wastewater resistome

N Makowska, A Philips, M Dabert, K Nowis, A Trzebny… - Water research, 2020 - Elsevier
… quantitatively β-lactamase and carbapenemase genes in the … of genes conferring resistance
to β-lactam and carbapenem … In the final effluent we found bacteria with genes that pose …

Rapid detection of carbapenemase genes by multiplex real-time PCR

J Monteiro, RH Widen, ACC Pignatari… - Journal of …, 2012 - academic.oup.com
… Some assays use multiplex real-time PCR to identify serine carbapenemase genes or
metallo-β-lactamase genes. Assays that target more than one class of carbapenemase (A, B and D…

[HTML][HTML] Multi-state study of Enterobacteriaceae harboring extended-spectrum beta-lactamase and carbapenemase genes in US drinking water

WD Tanner, JA VanDerslice, RK Goel, MK Leecaster… - Scientific reports, 2019 - nature.com
genes by multiplex PCR. Positive samples were subcultured to isolate organisms harboring
ESBL or carbapenemase genes… OXA-48 -type carbapenemase genes, including at least one …

Acquired carbapenem-hydrolyzing beta-lactamases and their genetic support

L Poirel, P Nordmann - Current pharmaceutical biotechnology, 2002 - ingentaconnect.com
… This review underlines the worldwide spread of carbapenem-hydrolyzing β-lactamases as
… of known class B carbapenemase genes. Detection of acquired class B enzymes may be …

[HTML][HTML] Carbapenemase-producing Enterobacteriaceae, US rivers

C Aubron, L Poirel, RJ Ash… - Emerging infectious …, 2005 - ncbi.nlm.nih.gov
… reservoir for carbapenemase genes. … of carbapenemase genes in enterobacterial strains
from rivers may have clinical importance. In the present study, the β-lactamase gene was …

[PDF][PDF] Carbapenem-hydrolyzing beta-lactamases

BA Rasmussen, K Bush - Antimicrobial agents and chemotherapy, 1997 - Am Soc Microbiol
… relevant -lactamases, an increasing number of carbapenem-… carbapenem class is the
market leader among parenteral -… -lactamase gene is identical to that of the metallo--lactamase

Biochemical properties of a carbapenem-hydrolyzing beta-lactamase from Enterobacter cloacae and cloning of the gene into Escherichia coli

P Nordmann, S Mariotte, T Naas, R Labia… - Antimicrobial agents …, 1993 - Am Soc Microbiol
… to 13-lactamlactamase genes commonly found in members of the family Enterobacteriaceae
(blaTEM-l and blasHv.3 derivatives), and with previously described carbapenemase genes