Potential of [18F]βCFT‐FE (2β‐carbomethoxy‐(4‐fluorophenyl)‐8‐(2‐[18F]fluoroethyl)nortropane) as a dopamine transporter ligand: A PET study in the …

N Harada, H Ohba, D Fukumoto, T Kakiuchi… - Synapse, 2004 - Wiley Online Library
… ]-CFT-FE) was synthesized and evaluated in comparison with [11C]-CFT in monkey brain
using animal positron emission tomography (PET). [18F]-CFT-FE and [11C]-CFT were injected …

Simplified synthesis of N‐(3‐[18F]fluoropropyl)‐2βcarbomethoxy3β‐(4‐fluorophenyl)nortropane ([18F]βCFT‐FP) using [18F]fluoropropyl tosylate as the …

T Koivula, O Perhola, EL Kämäräinen… - Journal of Labelled …, 2005 - Wiley Online Library
… 2β-carbomethoxy--(4-fluorophenyl)nortropane (nor-β-CFT). … % radiochemical yield of
[18F]β-CFT-FP (decay corrected to … overall radiochemical yield of [18F]β-CFT-FP in a shorter time…

Conformational analysis of cocaine, the potent analog 2β‐carbomethoxy‐(4‐fluorophenyl) tropane (CFT), and other dopamine reuptake blockers

M Froimowitz - Journal of computational chemistry, 1993 - Wiley Online Library
… hydrogen and the carbonyl of the carbomethoxy group. The N-… suggests that its carbomethoxy
may occupy the same region of … Under these conditions, the carbomethoxy group in CFT

Comparison of 2β-Carbomethoxy--(4-[18F]Fluorophenyl)Tropane and N-(3-[18F]Fluoropropyl)-2β-Carbomethoxy--(4-Fluorophenyl)Nortropane, Tracers for …

P Marjamäki, M Haaparanta, S Forsback… - Molecular imaging and …, 2010 - Springer
… In the present study, the accumulation of both [ 18 F]β-CFT and [ 18 F]β-CFT-FP in the
striatum was significantly decreased in rats pre-treated with GBR12909, which indicates that the …

Ex vivo evaluation of N-(3-[18F] fluoropropyl)-2β-carbomethoxy--(4-fluorophenyl) nortropane in rats

T Koivula, P Marjamäki, M Haaparanta… - Nuclear medicine and …, 2008 - Elsevier
… 18 F]β-CFT-FE possesses … -carbomethoxy--(4-fluorophenyl)nortropane ([ 18 F]β-CFT-FP)
accumulates in the rat striatum. Previously, our group demonstrated selectivity of [ 11 C]β-CFT

[PDF][PDF] Binding of the cocaine analog 2 beta-[3H] carboxymethoxy-3 beta-(4-fluorophenyl) tropane to the serotonin transporter.

G Rudnick, SC Wall - Molecular pharmacology, 1991 - researchgate.net
… These results suggest that imipramine and CFT bind to the … [‘H]CFT binding over a
range of CFT concentrations. … CFT. The transport rate in the absence of Na (7.38 pmol/mg/min) …

… the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2α‐carbomethoxy‐3α‐(4‐fluorophenyl …

N Chen, LL Sun, MEA Reith - Journal of neurochemistry, 2002 - Wiley Online Library
… analog of cocaine, 2β-carbomethoxy--(4fluorophenyl)tropane (CFT), and DA. DA binding
… [ 3 H]CFT binding. We sought to distinguish cationic interactions with CFT binding from those …

Cationic and Anionic Requirements for the Binding of 2β‐Carbomethoxy‐(4‐Fluorophenyl)[3H]tropane to the Dopamine Uptake Carrier

MEA Reith, LL Coffey - Journal of neurochemistry, 1993 - Wiley Online Library
… of 2~-carbomethoxy-3P-(4-fluorophenyl)[3H]tropane ([3H]CFT) binding to the dopamine
transporter in the rat striatum. The results indicate that [3H]CFT … K+ strongly decreased [3H]CFT

Preparation of [18F]βCFT‐FP and [11C]βCFT‐FP, selective radioligands for visualisation of the dopamine transporter using positron emission tomography (PET)

EL Kämäräinen, T Kyllönen… - Journal of Labelled …, 2000 - Wiley Online Library
… Altogether it is suggested that ß-CFT-FP should have a … We report the labelling of ß-CFT-FP
with fluorine-18 or carbon-11 … , 2f-carbomethoxy-3-(4fluorophenyl)nortropane (nor-B-CFT) (II) …

The Influence of Residual Nor-β-CFT in 11C CFT Injection on the Parkinson Disease Diagnosis: A: 11: C CFT PET Study

T Huang, H Wang, G Tang, X Liang, X Shi… - Clinical Nuclear …, 2012 - journals.lww.com
… is generally synthesized from the reaction of 2β-carbo-methoxy--(4-fluorophenyl)nortropane
(nor-β-CFT) as a precursor compound with 11-CH 3 OTf using high performance liquid …