… Spealman et al. showed that 2-β-carbomethoxy-3-β-(4-fluorophenyl)tropane (β-CFT, WIN …
binding ratio of β-CFT was measured with the 3 H-labeled β-CFT. [ 3 H]β-CFT was considered …

… The IC values for [3H]CFT binding sites are from Table 1 of the present study; the IC values
for [3H]cocaine binding sites are from Table 1 of Ref. 7. The individual drugs are coded as …

… [ 11 C]β-CFT is widely used to study DAT in animal models of … C]β-CFT is more
commonly seen in the literature, as the precursor used for radiolabeling, nor-β-CFT [2β-carbomethoxy-3β-(…

… 基 鄄N鄄2茁鄄甲 基 酯 鄄3茁鄄渊 4鄄氟 鄄苯 基 冤托 烷 渊 11C鄄methyl鄄N鄄2茁鄄
carbomethoxy鄄3茁鄄渊 4鄄fluo鄄 rophenyl冤鄄tropanel袁 11C鄄茁鄄CFT冤PET 显 像 可 以 准 确 尧 …

… We present the electrophilic synthesis of [ 18 F]2β-carbomethoxy-3β-(4-fluoro)tropane [[
18 F]CFT] and the pharmacological specificity and selectivity of [ 18 F]CFT for monoamine …

… 9 All seven stereoisomers of (lR)-cocaine show a 60-fold or greater reduction in potency for
inhibiting [3H] CFT binding. The inversion of the configuration (1S)-cocaine vs (lfi)-cocaine (1…

… DAT structures contributing to cocaine analog, cFT (2β carbomethoxy 3β (4 fluoro phenyl) …
discrete site for cFT binding is still to be determined. We previously reported that cFT binding is …

… The purpose of this study is to evaluate the efficacy of 11 C-CFT PET combined with 18 F-…
C-CFT PET combined with 18 F-FDG PET. We will exclude the combination of 11 C-CFT PET, …

Imaging techniques are increasingly applied to neuro-chemical and neuropharmacological
studies of brain function. PET (positron emission tomography) and SPECT (single photon …

… -induced higher levels of uptake of [11C]-CFT and [11C]-CIT-FE into … Not only [11C]-CIT-FE
but also [11C]-CFT reached the … availability as measured with [11C]-CFT and [11C]-CITFE in …